Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 2/20 | 0.49 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.48 |
| ▸ | CPA1 | P15085 | 2/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4608578 | 1.00 | ALDH1A1 (0.56) | ALDH1A1ACECA2MMEGPR34 | |
| SCHEMBL4608581 | 1.00 | ALDH1A1 (0.56) | ALDH1A1ACECA2MMEGPR34 | |
| SCHEMBL30118364 | 0.95 | ALDH1A1 (0.52) | ALDH1A1ACECA2MMEGPR34 | |
| SCHEMBL24711923 | 0.86 | NOS2 (0.46) | ALDH1A1ACECA2CPA1CA12 | |
| SCHEMBL14942929 | 0.86 | NOS2 (0.46) | ALDH1A1ACECA2CPA1CA12 | |
| SCHEMBL12668881 | 0.86 | NOS2 (0.46) | ALDH1A1ACECA2CPA1CA12 | |
| SCHEMBL27488809 | 0.84 | MMP1 (0.51) | ALDH1A1ACEMMECA12CA7 | |
| SCHEMBL6318078 | 0.84 | MMP1 (0.51) | ALDH1A1ACEMMECA12CA7 | |
| SCHEMBL8373966 | 0.84 | ALDH1A1 (0.57) | ALDH1A1ACECA2MMEGPR34 | |
| SCHEMBL22290826 | 0.84 | ALDH1A1 (0.57) | ALDH1A1ACECA2MMEGPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071329-A1 | METHODS FOR IDENTIFYING COMPOUNDS OF INTEREST USING ENCODED LIBRARIES | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | US | disclosed |
| US-20110251089-A1 | METHODS FOR SYNTHESIS OF ENCODED LIBRARIES | GLAXOSMITHKLINE (US) | 2011-10-13 | — | — | US | disclosed |
| US-7989395-B2 | Methods for identifying compounds of interest using encoded libraries | GLAXOSMITHKLINE LLC (US) | 2011-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251089-A1 | METHODS FOR SYNTHESIS OF ENCODED LIBRARIES | RNGTT, DTYMK, DUT | ALDH1A1 2470/4885ACE 421/4885CA2 4273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.