SCHEMBL4608581

SCHEMBL4608581

CN[C@@H](Cc1ccc(F)cc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
ACE P12821 2/20 0.54
CA2 P00918 1/20 0.51
MME P08473 2/20 0.49
GPR34 Q9UPC5 2/20 0.48
CPA1 P15085 2/20 0.47
ACE2 Q9BYF1 1/20 0.47
FOLH1 Q04609 1/20 0.46
CA12 O43570 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
POLB P06746 1/20 0.46
KMT2A Q03164 1/20 0.46
NOS3 P29474 1/20 0.46
NOS1 P29475 1/20 0.46
NOS2 P35228 1/20 0.46
PPARG P37231 1/20 0.45
CTSS P25774 1/20 0.45
CTSK P43235 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL805199 1.00 ALDH1A1 (0.56) ALDH1A1ACECA2MMEGPR34
SCHEMBL4608578 1.00 ALDH1A1 (0.56) ALDH1A1ACECA2MMEGPR34
SCHEMBL30118364 0.95 ALDH1A1 (0.52) ALDH1A1ACECA2MMEGPR34
SCHEMBL24711923 0.86 NOS2 (0.46) ALDH1A1ACECA2CPA1CA12
SCHEMBL14942929 0.86 NOS2 (0.46) ALDH1A1ACECA2CPA1CA12
SCHEMBL12668881 0.86 NOS2 (0.46) ALDH1A1ACECA2CPA1CA12
SCHEMBL27488809 0.84 MMP1 (0.51) ALDH1A1ACEMMECA12CA7
SCHEMBL6318078 0.84 MMP1 (0.51) ALDH1A1ACEMMECA12CA7
SCHEMBL8373966 0.84 ALDH1A1 (0.57) ALDH1A1ACECA2MMEGPR34
SCHEMBL22290826 0.84 ALDH1A1 (0.57) ALDH1A1ACECA2MMEGPR34

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122028793-A Fungicidal compositions 先正达农作物保护股份公司 2026-05-12 CN claimed
WO-2025032051-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-02-13 WO claimed
WO-2025032052-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-02-13 WO claimed
WO-2025032053-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-02-13 WO claimed
CN-118265452-A Fungicidal compositions 先正达农作物保护股份公司 2024-06-28 CN claimed
EP-4127157-A1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2023-02-08 EP claimed
CN-115697055-A Fungicidal compositions 先正达农作物保护股份公司 2023-02-03 CN claimed
CN-115697056-A Fungicidal compositions 先正达农作物保护股份公司 2023-02-03 CN claimed
CN-115666238-A Fungicidal compositions 先正达农作物保护股份公司 2023-01-31 CN claimed
CN-115666240-A Fungicidal compositions 先正达农作物保护股份公司 2023-01-31 CN claimed
WO-2021194908-A1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2021-09-30 WO claimed
US-10954287-B2 Ras binding peptides and methods of use RA PHARMACEUTICALS, INC. (US) 2021-03-23 US claimed
US-20190119358-A1 RAS BINDING PEPTIDES AND METHODS OF USE RA PHARMACEUTICALS, INC. 2019-04-25 US claimed
US-20170137468-A1 MODULATION OF COMPLEMENT ACTIVITY UCB HOLDINGS, INC. 2017-05-18 US claimed
EP-3154561-A2 MODULATION OF COMPLEMENT ACTIVITY RA Pharmaceuticals, Inc. (US) 2017-04-19 EP claimed
CN-106456701-A Modulation of complement activity RA制药公司 2017-02-22 CN claimed
WO-2015191951-A2 MODULATION OF COMPLEMENT ACTIVITY RA PHARMACEUTICALS, INC. (US) 2015-12-17 WO claimed
US-20150166606-A1 PEPTIDE AND PEPTIDOMIMETIC INHIBITORS RA PHARMACEUTICALS, INC. 2015-06-18 US claimed
EP-2850095-A1 PEPTIDE AND PEPTIDOMIMETIC INHIBITORS RA Pharmaceuticals, Inc. (US) 2015-03-25 EP claimed
WO-2013172954-A1 PEPTIDE AND PEPTIDOMIMETIC INHIBITORS RA PHARMACEUTICALS, INC (US) 2013-11-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170137468-A1 MODULATION OF COMPLEMENT ACTIVITY C5, C3AR1, CFH ALDH1A1 3629/4885ACE 266/4885CA2 4272/4885
US-20150166606-A1 PEPTIDE AND PEPTIDOMIMETIC INHIBITORS KLKB1, KLK1, KLK5 ALDH1A1 4182/4885ACE 113/4885CA2 2333/4885
US-10954287-B2 Ras binding peptides and methods of use KRAS, RASGRP1, NRAS ALDH1A1 4777/4885ACE 1198/4885CA2 3649/4885
US-20190119358-A1 RAS BINDING PEPTIDES AND METHODS OF USE KRAS, RASGRP1, NRAS ALDH1A1 4777/4885ACE 1198/4885CA2 3649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.