Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL974470 | 0.83 | HSD11B1 (0.47) | HSD11B1TSHRL3MBTL1TDP1POLB | |
| SCHEMBL28730355 | 0.82 | HSD11B1 (0.50) | HSD11B1TSHRL3MBTL1TDP1POLB | |
| SCHEMBL7557125 | 0.78 | HSD11B1 (0.50) | HSD11B1TSHRL3MBTL1TDP1POLB | |
| SCHEMBL8042370 | 0.77 | CES1 (0.42) | HSD11B1TSHRL3MBTL1TDP1POLB | |
| SCHEMBL9026301 | 0.77 | HSD11B1 (0.46) | HSD11B1TSHRL3MBTL1TDP1POLB | |
| SCHEMBL28263941 | 0.76 | L3MBTL1 (0.45) | HSD11B1TSHRL3MBTL1TDP1POLB | |
| SCHEMBL64274 | 0.75 | TDP1 (0.52) | HSD11B1TSHRL3MBTL1TDP1POLB | |
| SCHEMBL3720381 | 0.75 | TDP1 (0.52) | HSD11B1TSHRL3MBTL1TDP1POLB | |
| SCHEMBL8135824 | 0.74 | GAA (0.46) | HSD11B1TSHRL3MBTL1TDP1POLB | |
| SCHEMBL29187671 | 0.74 | HSD11B1 (0.51) | HSD11B1TSHRL3MBTL1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106164181-A | Azo compound, and dye-type polarizing film and polarizing plate containing the same | 日本化药株式会社 | 2016-11-23 | — | — | CN | disclosed |
| CN-1211384-C | Thiadiazolyl and oxadiazolyl phenyl oxazolidinone antibacterial agent | UPJOHN CO (US) | 2005-07-20 | — | — | CN | disclosed |
| CN-1261889-A | Thiadiazolyl and oxadiazolyl phenyl oxazolidinone antibacterial agent | UPJOHN CO (US) | 2000-08-02 | — | — | CN | disclosed |