SCHEMBL27489704

SCHEMBL27489704

C=Cc1ccc(C2=NCCS2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.43
LMNA P02545 1/20 0.43
ALDH1A1 P00352 3/20 0.41
MAPT P10636 1/20 0.40
ATM Q13315 1/20 0.40
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
CASP3 P42574 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
MGLL Q99685 3/20 0.38
TSHR P16473 1/20 0.32
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
DAPK3 O43293 1/20 0.30
JAK2 O60674 1/20 0.30
ABL1 P00519 1/20 0.30
NTRK1 P04629 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21664123 0.75 ALDH1A1 (0.47) SMN1; SMN2LMNAALDH1A1MAPTATM
SCHEMBL1147751 0.74 LMNA (0.53) SMN1; SMN2LMNAALDH1A1MAPTATM
SCHEMBL21663870 0.72 MAPT (0.48) SMN1; SMN2LMNAALDH1A1MAPTATM
SCHEMBL14875014 0.69 SMN1; SMN2 (0.42) SMN1; SMN2LMNAALDH1A1MAPTATM
SCHEMBL14875025 0.67 G6PD (0.49) SMN1; SMN2LMNAALDH1A1MAPTATM
SCHEMBL21937222 0.67 ALDH1A1 (0.52) ALDH1A1MAPTTSHRDAPK3JAK2
SCHEMBL593791 0.67 ALDH1A1 (0.79) ALDH1A1MAPTMGLLTSHRDAPK3
SCHEMBL583978 0.67 ALDH1A1 (0.79) ALDH1A1MAPTMGLLTSHRDAPK3
Water SCHEMBL7178879 0.65 ALDH1A1 (0.73) ALDH1A1MAPTMGLLTSHRDAPK3
SCHEMBL473081 0.64 ALDH1A1 (1.00) ALDH1A1MAPTTSHRDAPK3JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1247667-C Crossliking method of alkyl styrene polymer and composite containing said polymer EXXON MOBIL CHEM PATENTS INC (US) 2006-03-29 CN disclosed
CN-1495221-A Crossliking method of alkyl styrene polymer and composite containing said polymer ����ɭ���ڻ�ѧר����˾ 2004-05-12 CN disclosed
CN-1133658-C Alkenylsilane Functionalization of Alkylstyrene Homopolymers and Copolymers ����ɭ���ڻ�ѧר����˾ 2004-01-07 CN disclosed
CN-1241194-A Alkenylsilane Functionalization of Alkylstyrene Homopolymers and Copolymers EXXON CHEMICAL PATENTS INC (US) 2000-01-12 CN disclosed