Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27368504 | 0.86 | LMNA (0.58) | LMNASMN1; SMN2POLBALDH1A1MAPT | |
| SCHEMBL21663870 | 0.80 | MAPT (0.48) | LMNASMN1; SMN2ALDH1A1MAPTATM | |
| SCHEMBL20411019 | 0.78 | ALDH1A1 (0.43) | LMNASMN1; SMN2ALDH1A1MAPTATM | |
| SCHEMBL8378973 | 0.78 | MGLL (0.43) | LMNASMN1; SMN2ALDH1A1MAPTATM | |
| SCHEMBL21664123 | 0.78 | ALDH1A1 (0.47) | LMNASMN1; SMN2ALDH1A1MAPTATM | |
| SCHEMBL5777989 | 0.78 | ALDH1A1 (0.43) | LMNASMN1; SMN2ALDH1A1MAPTATM | |
| SCHEMBL6170485 | 0.78 | CYP2A6 (0.50) | LMNASMN1; SMN2ALDH1A1MAPTATM | |
| SCHEMBL27886244 | 0.77 | ALDH1A1 (0.60) | LMNASMN1; SMN2ALDH1A1MAPTATM | |
| SCHEMBL27605025 | 0.77 | LMNA (0.56) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL28434848 | 0.77 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2ALDH1A1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100404540-C | Thiazolo-, oxazolo-and imidazoquinazoline compounds which inhibit protein kinases | CYCLACEL LTD (GB) | 2008-07-23 | — | — | CN | claimed |
| CN-1849325-A | Thiazolo-, oxazalo and imidazolo-quinazoline compounds capable of inhibiting prot ein kinases | CYCLACEL LTD (GB) | 2006-10-18 | — | — | CN | claimed |
| US-6955921-B2 | Trypsin substrate and diagnostic device, and method of using same | BAYER CORPORATION (US) | 2005-10-18 | — | — | US | claimed |
| EP-1529037-A2 | SYNTHESIS OF 2-ALKYLCYSTEINES, 2-(HYDROXYLATED PHENYL)-4-ALKYLTHIAZOLINE-4-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | Genzyme Corporation (US) | 2005-05-11 | — | — | EP | claimed |
| US-6770764-B2 | DIAGNOSIS OF BACTERIA INFECTIONS | BAYER CORPORATION | 2004-08-03 | — | — | US | claimed |
| US-20030236404-A1 | Synthesis of 2-alkylcysteine via phase transfer catalysis | GENZYME CORPORATION | 2003-12-25 | — | — | US | claimed |
| WO-2003097622-A2 | SYNTHESIS OF 2-ALKYLCYSTEINES, 2-(HYDROXYLATED PHENYL)-4-ALKYLTHIAZOLINE-4-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | GENZYME CORPORATION (US) | 2003-11-27 | — | — | WO | claimed |
| US-20030125577-A1 | Trypsin substrate and diagnostic device, and method of using same | SIEMENS HEALTHCARE DIAGNOSTICS INC. | 2003-07-03 | — | — | US | claimed |
| US-20020004219-A1 | Trypsin substrate and diganostic device, and method of using same | SIEMENS HEALTHCARE DIAGNOSTICS INC. | 2002-01-10 | — | — | US | claimed |
| EP-1157984-A2 | Trypsin substrate and diagnostic device, and method of using same | Bayer Corporation (US) | 2001-11-28 | — | — | EP | claimed |
| EP-0432661-B1 | 2-Substituted phenyl-2-oxazoline or thiazoline derivatives, process for producing the same and insecticides and acaricides containing the same | YASHIMA KAGAKU KOGYO KK (JP) | 1996-03-06 | — | — | EP | claimed |
| EP-0432661-A2 | 2-Substituted phenyl-2-oxazoline or thiazoline derivatives, process for producing the same and insecticides and acaricides containing the same | YASHIMA CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1991-06-19 | — | — | EP | claimed |
| CN-119776090-A | Soft endoscope strong-effect multienzyme cleaning agent and preparation process thereof | 杭州西子卫生消毒药械有限公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-114805348-A | Triazolopyridine amide compound and preparation method and application thereof | 贵州大学 | 2022-07-29 | — | — | CN | disclosed |
| US-11342511-B2 | Azoline ring-containing compound, electron transport/injection layer material containing the same, and organic electroluminescent element using the same | SK MATERIALS JNC CO., LTD. (KR) | 2022-05-24 | — | — | US | disclosed |
| US-11319347-B2 | Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound | FUJIFILM CORPORATION (JP) | 2022-05-03 | — | — | US | disclosed |
| EP-0203359-A2 | Novel peptide having dentinal fluid transport stimulating activity | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1986-12-03 | — | — | EP | disclosed |
| EP-0132165-A1 | Adsorbable alkynyl substituted heterocyclic quaternary ammonium salts and applications thereof to silver halide photography | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-01-23 | — | — | EP | disclosed |
| US-4471044-A | Silver halide emulsions and photographic elements containing adsorbable alkynyl substituted heterocyclic quaternary ammonium salts | EASTMAN KODAK COMPANY (US) | 1984-09-11 | — | — | US | disclosed |
| US-4115122-A | Internal latent image silver halide emulsion containing a heterocyclic quaternary salt having a propargyl or a butyryl containing substituent | FUJI PHOTO FILM CO., LTD. (JP) | 1978-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020004219-A1 | Trypsin substrate and diganostic device, and method of using same | PRSS3, CTRL, PRSS2 | LMNA 1790/4885SMN1; SMN2 4365/4885POLB 2537/4885 |
| US-20030236404-A1 | Synthesis of 2-alkylcysteine via phase transfer catalysis | DIMT1, ICMT, CNDP2 | LMNA 4323/4885SMN1; SMN2 2739/4885POLB 4039/4885 |
| US-11342511-B2 | Azoline ring-containing compound, electron transport/injection layer material containing the same, and organic electroluminescent element using the same | SLC7A5, EML4, ARNT | LMNA 1407/4885SMN1; SMN2 3753/4885POLB 3289/4885 |
| US-11319347-B2 | Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound | VIP, NPPA, NGLY1 | LMNA 3026/4885SMN1; SMN2 3728/4885POLB 4749/4885 |
| US-20030125577-A1 | Trypsin substrate and diagnostic device, and method of using same | CTRL, PRSS3, SPINT2 | LMNA 1936/4885SMN1; SMN2 3309/4885POLB 2333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.