Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 3/20 | 0.44 |
| ▸ | PNMT | P11086 | 2/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11666754 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2KCNN4MMP12ADRA2AADRA2B | |
| SCHEMBL1844578 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2KCNN4MMP12ADRA2AADRA2B | |
| SCHEMBL29420719 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2KCNN4MMP12ADRA2AADRA2B | |
| SCHEMBL218213 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2KCNN4MMP12ADRA2AADRA2B | |
| SCHEMBL10438953 | 0.81 | SMN1; SMN2 (0.36) | SMN1; SMN2PNMTKCNN4MMP12 | |
| SCHEMBL961056 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2KCNN4MMP12ADRA2AADRA2B | |
| SCHEMBL381604 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2KCNN4MMP12ADRA2AADRA2B | |
| SCHEMBL18716521 | 0.78 | AKR1B1 (0.43) | SMN1; SMN2KCNN4 | |
| SCHEMBL29825088 | 0.77 | ALDH1A1 (0.44) | SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C | |
| SCHEMBL7452092 | 0.77 | ALDH1A1 (0.44) | SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106831734-B | A kind of and agromycin A total synthesis method | 中国医学科学院医药生物技术研究所 | 2019-09-03 | — | — | CN | claimed |
| CN-103003231-A | Novel method for preparing phenylcyclopropylamine derivatives and use thereof for preparing ticagrelor | ACTAVIS GROUP PTC EHF | 2013-03-27 | — | — | CN | disclosed |
| CN-1259322-C | Asymmetric copper compound and cyclopropanation reaction with it | SUMITOMO CHEMICAL CO (JP) | 2006-06-14 | — | — | CN | disclosed |
| CN-1231456-C | Process for preparing optically active cyclopropyl carboxylic acid derivative | SUMITOMO CHEMICAL CO (JP) | 2005-12-14 | — | — | CN | disclosed |
| CN-1480448-A | Process for preparing optically active cyclopropyl carboxylic acid derivative | ס�ѻ�ѧ��ҵ��ʽ���� | 2004-03-10 | — | — | CN | disclosed |
| CN-1134422-C | Optically active bisoxazoline compounds, process for their preparation and their use | ������������ʽ���� | 2004-01-14 | — | — | CN | disclosed |
| CN-1384105-A | Asymmetric copper compound and cyclopropanation reaction with it | SUMITOMO CHEMICAL CO (JP) | 2002-12-11 | — | — | CN | disclosed |
| CN-1210858-A | Optically active bisoxazoline compounds, process for their preparation and their use | SUMITOMO CHEMICAL CO (JP) | 1999-03-17 | — | — | CN | disclosed |