Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.33 |
| ▸ | TUBB | P07437 | 2/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1844578 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2ADRA2AADRA2BADRA2CKCNN4 | |
| SCHEMBL27489840 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2ADRA2AADRA2BADRA2CKCNN4 | |
| SCHEMBL218213 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2ADRA2AADRA2BADRA2CKCNN4 | |
| SCHEMBL29420719 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2ADRA2AADRA2BADRA2CKCNN4 | |
| SCHEMBL18716521 | 0.81 | AKR1B1 (0.43) | SMN1; SMN2KCNN4 | |
| SCHEMBL961056 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2ADRA2AADRA2BADRA2CKCNN4 | |
| SCHEMBL381604 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2ADRA2AADRA2BADRA2CKCNN4 | |
| SCHEMBL8855966 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2ADRA2AADRA2BADRA2CKCNN4 | |
| SCHEMBL961794 | 0.77 | ADRA2A (0.48) | SMN1; SMN2ADRA2AADRA2BADRA2CKCNN4 | |
| SCHEMBL31325259 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2ADRA2AADRA2BADRA2CKCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4092326-A | Process for production of substituted oxazolines | IMC CHEMICAL GROUP, INC. (US) | 1978-05-30 | — | — | US | disclosed |
| US-4092326-A | Process for production of substituted oxazolines | IMC CHEMICAL GROUP, INC. (US) | 1978-05-30 | — | — | US | disclosed |