SCHEMBL29420719

SCHEMBL29420719

c1ccc(C2=NCCO2)c(C2=NCCO2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.50
KCNN4 O15554 1/20 0.44
ADRA2A P08913 2/20 0.39
ADRA2B P18089 2/20 0.39
ADRA2C P18825 2/20 0.39
MMP12 P39900 1/20 0.38
ITGB2 P05107 1/20 0.35
ICAM1 P05362 1/20 0.35
ITGAL P20701 1/20 0.35
TUBB4A P04350 3/20 0.34
TUBB P07437 3/20 0.34
TUBA3C P0DPH7 3/20 0.34
TUBA1B P68363 3/20 0.34
TUBA4A P68366 3/20 0.34
TUBB4B P68371 3/20 0.34
TUBB3 Q13509 3/20 0.34
TUBB2A Q13885 3/20 0.34
TUBB8 Q3ZCM7 3/20 0.34
TUBA3E Q6PEY2 3/20 0.34
TUBA1A Q71U36 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218213 1.00 SMN1; SMN2 (0.50) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL381604 0.98 SMN1; SMN2 (0.49) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL961794 0.90 ADRA2A (0.48) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL8855966 0.86 SMN1; SMN2 (0.55) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL2572924 0.86 NOS3 (0.41) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL25218345 0.86 SMN1; SMN2 (0.44) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL7452092 0.86 ALDH1A1 (0.44) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL8638335 0.86 SMN1; SMN2 (0.44) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL7831181 0.86 NISCH (0.44) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL31048511 0.86 NISCH (0.44) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114835871-A Biodegradable block copolyester and synthesis method thereof 惠州博科环保新材料有限公司 2022-08-02 CN claimed
CN-114805764-A Biodegradable block copolyester and synthesis method thereof 惠州博科环保新材料有限公司 2022-07-29 CN claimed
EP-4709772-A1 REACTIVE COMPOSITIONS THAT INCLUDE ACID FUNCTIONAL COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM PPG Industries Ohio Inc. (US) 2026-03-18 EP disclosed
EP-4696136-A2 PEST MONITORING SYSTEM WITH CONDUCTIVE ELECTRODES BASF CORPORATION (US) 2026-02-18 EP disclosed
EP-4688951-A1 POLYESTERBLEND FOR HOME COMPOSTABLE APPLICATIONS BASF SE (DE) 2026-02-11 EP disclosed
EP-3648594-B1 PEST MONITORING SYSTEM WITH CONDUCTIVE ELECTRODES BASF CORP (US) 2025-09-10 EP disclosed
EP-4608916-A1 BIODEGRADABLE POLYMER COMPOSITION BASF SE (DE) 2025-09-03 EP disclosed
CN-120153026-A Biodegradable polymer composition 巴斯夫欧洲公司 2025-06-13 CN disclosed
CN-120118294-A Aliphatic polyester, polyester composition containing same and application of aliphatic polyester 金发科技股份有限公司 2025-06-10 CN disclosed
CN-120118293-A Aliphatic polyester and application thereof 金发科技股份有限公司 2025-06-10 CN disclosed
CN-114957630-B Semi-aromatic polyester and preparation method and application thereof 珠海金发生物材料有限公司 2025-03-25 CN disclosed
CN-110997830-B White inkjet ink composition for printing 阪田油墨股份有限公司 2022-07-26 CN disclosed
WO-2022154000-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2022-07-21 WO disclosed
CN-114761866-A Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal display element, and method for producing liquid crystal display element 日产化学株式会社 2022-07-15 CN disclosed
EP-4021955-A1 PHOTOCHROMIC COMPOSITION WITH POLYOL AND POLY(ANHYDRIDE) Transitions Optical, Ltd. (IE) 2022-07-06 EP disclosed
EP-4022366-A1 PHOTOCHROMIC FILM LAMINATE Transitions Optical, Ltd. (IE) 2022-07-06 EP disclosed
WO-2022124332-A1 RESIN COMPOSITION, PELLET, MOLDED ARTICLE AND METHOD FOR PRODUCING RESIN COMPOSITION 三菱エンジニアリングプラスチックス株式会社 2022-06-16 WO disclosed
EP-2660295-B1 Metal article coated with a composition comprising olefinic double bonds EVONIK OPERATIONS GMBH (DE) 2022-06-08 EP disclosed
CN-114174427-A Flame-retardant polybutylene terephthalate resin composition 宝理塑料株式会社 2022-03-11 CN disclosed
EP-3953141-A1 POLYBUTYLENE TEREPHTHALATE THERMOFORMING PROCESS BASF SE (DE) 2022-02-16 EP disclosed