Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
| ▸ | HTR3B | O95264 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092369 | 0.85 | KDM4E (0.58) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL28945745 | 0.85 | KDM4E (0.58) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL10775133 | 0.84 | KDM4E (0.56) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL10775129 | 0.84 | KDM4E (0.56) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL12480511 | 0.84 | KDM4E (0.56) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL7493746 | 0.74 | KDM4E (0.55) | SIGMAR1ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL6301700 | 0.74 | SIGMAR1 (0.42) | SIGMAR1ALDH1A1KDM4EMEN1HPGD | |
| Phenylpiperazine SCHEMBL11621472 | 0.73 | ADRB1 (0.83) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| Phenylpiperazine SCHEMBL11770718 | 0.71 | HTR3E (0.57) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL2789419 | 0.71 | KMT2A (0.52) | ALDH1A1KDM4EMEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1209744-A | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1999-03-03 | — | — | CN | disclosed |