Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 4/20 | 0.43 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27657643 | 0.83 | HCAR3 (0.44) | HCAR3KDM4EMAPK1ALDH1A1HTT | |
| SCHEMBL3154313 | 0.78 | THRB (0.44) | ALDH1A1MAPT | |
| SCHEMBL30018445 | 0.77 | ALDH1A1 (0.58) | HCAR3S100A4TRPV1KDM4EMAPK1 | |
| SCHEMBL6506822 | 0.77 | ALDH1A1 (0.58) | HCAR3S100A4TRPV1KDM4EMAPK1 | |
| SCHEMBL3000565 | 0.75 | TSHR (0.40) | HCAR3S100A4TRPV1KDM4EMAPK1 | |
| SCHEMBL652038 | 0.74 | HCAR3 (0.44) | HCAR3S100A4TRPV1KDM4EABCB1 | |
| SCHEMBL652037 | 0.74 | HCAR3 (0.44) | HCAR3S100A4TRPV1KDM4EABCB1 | |
| SCHEMBL17309819 | 0.73 | ALDH3A1 (0.63) | HCAR3S100A4TRPV1KDM4EMAPK1 | |
| SCHEMBL3498660 | 0.72 | KDM4E (0.45) | S100A4TRPV1KDM4EABCB1ABCC1 | |
| SCHEMBL30025405 | 0.72 | KDM4E (0.45) | S100A4TRPV1KDM4EABCB1ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1177831-C | Novel benzimidazolone-benzoxazolone-or benzothiazolone derivatives as modulators of ion channels | 神经研究公司 | 2004-12-01 | — | — | CN | disclosed |
| CN-1329601-A | Novel benzimidazolone-benzoxazolone-or benzothiazolone derivatives as modulators of ion channels | NEUROSEARCH AS (DK) | 2002-01-02 | — | — | CN | disclosed |