Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.46 |
| ▸ | ITGAV | P06756 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27511351 | 0.84 | ALDH1A1 (0.50) | GAANPC1RAB9APKMCYP1A2 | |
| SCHEMBL27509166 | 0.83 | NPC1 (0.58) | GAANPC1RAB9ATP53PKM | |
| SCHEMBL27509893 | 0.83 | NPC1 (0.58) | GAANPC1RAB9ATP53PKM | |
| SCHEMBL28741340 | 0.83 | NPC1 (0.58) | GAANPC1RAB9ATP53PKM | |
| SCHEMBL27511699 | 0.81 | ITGB3 (0.52) | F2NPC1RAB9APKMHPGD | |
| SCHEMBL11181798 | 0.80 | KMT2A (0.61) | F2GAANPC1RAB9ATP53 | |
| SCHEMBL27557417 | 0.76 | GAA (0.51) | GAANPC1RAB9ATP53PKM | |
| SCHEMBL4575591 | 0.74 | KMT2A (0.68) | F2GAANPC1RAB9ATP53 | |
| SCHEMBL28475782 | 0.73 | F2 (0.69) | F2GAANPC1RAB9ATP53 | |
| SCHEMBL24254588 | 0.72 | F2 (0.60) | F2GAANPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1223650-A | Piperidines and pyrrolidines | MERCK PATENT GMBH (DE) | 1999-07-21 | — | — | CN | disclosed |