Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.45 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2331452 | 0.85 | MEN1 (0.55) | ADORA3MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL25389290 | 0.84 | ADORA3 (0.62) | ADORA3MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL31179635 | 0.84 | ADORA3 (0.50) | ADORA3MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL28824893 | 0.81 | KDM4E (0.52) | ADORA3MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL31584712 | 0.79 | ADORA3 (1.00) | ADORA3MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL87774 | 0.79 | ADORA3 (1.00) | ADORA3MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL27740532 | 0.77 | ADORA3 (0.45) | ADORA3MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL27915695 | 0.77 | TTR (0.44) | ADORA3MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL28807085 | 0.74 | ALDH1A1 (0.50) | ADORA3MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL49552 | 0.72 | MAOA (0.63) | ADORA3CYP3A4MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1217698-C | Activation and protection of T-cells (CD4+ and CD8+) using and H2 receptor agonist and other T-cell activating agents | MAXIN PHARMACEUTICALS INC (US) | 2005-09-07 | — | — | CN | claimed |
| CN-1324245-A | Activation and protection of T-cells (CD4+ and CD8+) using and H2 receptor agonist and other T-cell activating agents | MAXIN PHARMACEUTICALS INC (US) | 2001-11-28 | — | — | CN | claimed |
| CN-1217698-C | Activation and protection of T-cells (CD4+ and CD8+) using and H2 receptor agonist and other T-cell activating agents | MAXIN PHARMACEUTICALS INC (US) | 2005-09-07 | — | — | CN | disclosed |
| CN-1324245-A | Activation and protection of T-cells (CD4+ and CD8+) using and H2 receptor agonist and other T-cell activating agents | MAXIN PHARMACEUTICALS INC (US) | 2001-11-28 | — | — | CN | disclosed |