SCHEMBL27495677

SCHEMBL27495677

C=Cc1ccccc1N1CCN(C(=O)CNC(=O)OC(C)(C)C)CC1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.55
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
TSHR P16473 1/20 0.47
DRD2 P14416 6/20 0.47
RAB9A P51151 1/20 0.46
RBP4 P02753 2/20 0.45
MAPK8 P45983 1/20 0.44
FNTA P49354 1/20 0.44
FNTB P49356 1/20 0.44
GFER P55789 2/20 0.42
MMP1 P03956 1/20 0.42
MMP9 P14780 1/20 0.42
MMP13 P45452 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7983470 0.84 SIGMAR1 (0.59) SIGMAR1KMT2AMEN1ALDH1A1TSHR
SCHEMBL10274715 0.83 RBP4 (0.66) SIGMAR1KMT2AMEN1ALDH1A1TSHR
SCHEMBL13039955 0.81 SIGMAR1 (0.59) SIGMAR1KMT2AMEN1ALDH1A1TSHR
SCHEMBL28742235 0.81 GPR119 (0.52) ALDH1A1
SCHEMBL7971897 0.80 SIGMAR1 (0.55) SIGMAR1KMT2AMEN1ALDH1A1TSHR
SCHEMBL14207195 0.76 GPR174 (0.48) SIGMAR1KMT2AMEN1ALDH1A1
SCHEMBL7421028 0.76 KDM4A (0.44) SIGMAR1KMT2AMEN1ALDH1A1RAB9A
SCHEMBL12206782 0.75 GAA (0.58) SIGMAR1KMT2AMEN1ALDH1A1TSHR
SCHEMBL27495676 0.75 SIGMAR1 (0.60) SIGMAR1KMT2AMEN1ALDH1A1TSHR
Hydrochloric Acid SCHEMBL27512921 0.74 KMT2A (0.45) SIGMAR1KMT2AMEN1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1223659-A Fused imidazopyridine derivatives as antihyperlipidemic agents TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1999-07-21 CN disclosed