Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.44 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1293285 | 0.86 | TSHR (0.57) | TSHRCASP1SMN1; SMN2 | |
| SCHEMBL2770320 | 0.84 | TSHR (0.68) | XDHTSHRCASP1SMN1; SMN2ERCC5 | |
| SCHEMBL3417670 | 0.80 | TSHR (0.70) | XDHADRB1ADRB3TSHRCASP1 | |
| SCHEMBL120353 | 0.80 | ACMSD (0.63) | XDHTSHRCASP1SMN1; SMN2ERCC5 | |
| SCHEMBL30784621 | 0.79 | XDH (0.60) | XDHTSHRCASP1SMN1; SMN2ERCC5 | |
| SCHEMBL18688873 | 0.79 | XDH (0.60) | XDHTSHRCASP1SMN1; SMN2ERCC5 | |
| SCHEMBL27259107 | 0.78 | KLKB1 (0.52) | TAAR1TSHRCASP1SMN1; SMN2USP28 | |
| SCHEMBL6496649 | 0.77 | AKR1C2 (0.68) | XDHTSHRCASP1SMN1; SMN2ERCC5 | |
| SCHEMBL4527705 | 0.77 | XDH (0.55) | XDHTSHRCASP1SMN1; SMN2ERCC5 | |
| SCHEMBL5558540 | 0.76 | TAAR1 (0.62) | TAAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1228327-C | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2005-11-23 | — | — | CN | disclosed |
| CN-1377336-A | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2002-10-30 | — | — | CN | disclosed |