Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 5/20 | 0.49 |
| ▸ | NMUR2 | Q9GZQ4 | 5/20 | 0.47 |
| ▸ | NMUR1 | Q9HB89 | 4/20 | 0.47 |
| ▸ | CTSD | P07339 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 4/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.43 |
| ▸ | CTSE | P14091 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8060131 | 0.87 | ACE (0.56) | RENNMUR2ACEACE2 | |
| SCHEMBL7411063 | 0.87 | ACE (0.56) | RENNMUR2ACEACE2 | |
| SCHEMBL2045662 | 0.85 | REN (0.54) | RENNMUR2NMUR1CTSDACE | |
| SCHEMBL7419554 | 0.85 | REN (0.54) | RENNMUR2NMUR1CTSDACE | |
| SCHEMBL5208748 | 0.78 | CTSD (0.49) | CTSDACEACE2CTSEBACE1 | |
| SCHEMBL8334047 | 0.77 | CALCRL (0.49) | RENNMUR2CTSDCTSEBACE1 | |
| SCHEMBL6374240 | 0.75 | OPRM1 (0.52) | ACEACE2 | |
| SCHEMBL15251857 | 0.74 | MEN1 (0.57) | ACEACE2ITGB1ITGA4 | |
| SCHEMBL15251858 | 0.74 | MEN1 (0.57) | ACEACE2ITGB1ITGA4 | |
| SCHEMBL30788009 | 0.74 | NMUR2 (0.53) | NMUR2NMUR1ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1193325-A | cell adhesion inhibitors | BIOGEN INC (US) | 1998-09-16 | — | — | CN | claimed |
| CN-1195778-C | cell adhesion inhibitors | BIOGEN INC (US) | 2005-04-06 | — | — | CN | disclosed |
| CN-1193325-A | cell adhesion inhibitors | BIOGEN INC (US) | 1998-09-16 | — | — | CN | disclosed |