Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978425 | 0.88 | CES2 (0.41) | ALBRXRACES2CES1BCHE | |
| SCHEMBL1758773 | 0.87 | ALDH1A1 (0.46) | ALBALDH1A1ALOX15KDM4EGAA | |
| SCHEMBL28973887 | 0.85 | ALDH1A1 (0.44) | ALBALDH1A1ALOX15KDM4EGAA | |
| SCHEMBL1479090 | 0.81 | ALDH1A1 (0.48) | ALBALDH1A1ALOX15KDM4EGAA | |
| SCHEMBL2361001 | 0.81 | GABRA1 (0.46) | ALDH1A1ALOX15KDM4EGAATSHR | |
| SCHEMBL2834426 | 0.80 | ALB (0.47) | ALBCES2CES1BCHEALDH1A1 | |
| SCHEMBL16429101 | 0.80 | ALB (0.59) | ALBCES2CES1BCHEALDH1A1 | |
| SCHEMBL461024 | 0.79 | MMP2 (0.50) | ALDH1A1ALOX15KDM4EGAATSHR | |
| SCHEMBL18929968 | 0.79 | ALDH1A1 (0.50) | RXRAALDH1A1ALOX15KDM4EERCC5 | |
| SCHEMBL4913415 | 0.79 | ALDH1A1 (0.39) | ALBALDH1A1ALOX15KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10707422-B2 | Production of organic phosphorescent layers with addition of heavy main group metal complexes | SIEMENS AKTIENGESELLSCHAFT (DE) | 2020-07-07 | — | — | US | claimed |
| EP-2999766-B1 | PRODUCTION OF ORGANIC PHOSPHORESCENT LAYERS WITH ADDITION OF HEAVY MAIN GROUP METAL COMPLEXES | SIEMENS AG (DE) | 2017-11-15 | — | — | EP | claimed |
| US-20160181540-A1 | Production Of Organic Phosphorescent Layers With Addition Of Heavy Main Group Metal Complexes | SIEMENS AKTIENGESELLSCHAFT (DE) | 2016-06-23 | — | — | US | claimed |
| EP-1546221-A4 | PHOTORESISTS, FLUORINATED POLYMERS AND PROCESSES FOR 157 nm MICROLITHOGRAPHY | DU PONT (US) | 2008-06-18 | — | — | EP | claimed |
| US-7264914-B2 | Fluorinated polymers having polycyclic groups with fused 4-membered carbocyclic rings, useful as photoresists, and processes for microlithography | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-09-04 | — | — | US | claimed |
| US-20050277052-A1 | Fluorinated polymers having polycyclic groups with fused 4-membered carbocyclic rings, useful as photoresists, and processes for microlithography | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-12-15 | — | — | US | claimed |
| EP-1546221-A2 | PHOTORESISTS, FLUORINATED POLYMERS AND PROCESSES FOR 157 nm MICROLITHOGRAPHY | E. I. du Pont de Nemours and Company (US) | 2005-06-29 | — | — | EP | claimed |
| WO-2004014964-A2 | PHOTORESISTS, FLUORINATED POLYMERS AND PROCESSES FOR 157 nm MICROLITHOGRAPHY | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-02-19 | — | — | WO | claimed |
| US-10707422-B2 | Production of organic phosphorescent layers with addition of heavy main group metal complexes | SIEMENS AKTIENGESELLSCHAFT (DE) | 2020-07-07 | — | — | US | disclosed |
| US-10336717-B2 | Inhibitors of beta-secretase | VITAE PHARMACEUTICALS, LLC (US) | 2019-07-02 | — | — | US | disclosed |
| US-10336717-B2 | Inhibitors of beta-secretase | VITAE PHARMACEUTICALS, LLC (US) | 2019-07-02 | — | — | US | disclosed |
| US-20160272600-A1 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, LLC | 2016-09-22 | — | — | US | disclosed |
| US-20160272600-A1 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, LLC | 2016-09-22 | — | — | US | disclosed |
| US-20160272600-A1 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, LLC | 2016-09-22 | — | — | US | disclosed |
| EP-1546221-B1 | FLUORINATED POLYMERS HAVING POLYCYCLIC GROUPS WITH FUSED 4-MEMBERED HETEROCYCLIC RINGS, USEFUL AS PHOTORESISTS, AND PROCESSES FOR MICROLITHOGRAPHY | DU PONT (US) | 2010-03-10 | — | — | EP | disclosed |
| EP-1546221-A4 | PHOTORESISTS, FLUORINATED POLYMERS AND PROCESSES FOR 157 nm MICROLITHOGRAPHY | DU PONT (US) | 2008-06-18 | — | — | EP | disclosed |
| US-7264914-B2 | Fluorinated polymers having polycyclic groups with fused 4-membered carbocyclic rings, useful as photoresists, and processes for microlithography | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-09-04 | — | — | US | disclosed |
| US-20050277052-A1 | Fluorinated polymers having polycyclic groups with fused 4-membered carbocyclic rings, useful as photoresists, and processes for microlithography | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-12-15 | — | — | US | disclosed |
| EP-1546221-A2 | PHOTORESISTS, FLUORINATED POLYMERS AND PROCESSES FOR 157 nm MICROLITHOGRAPHY | E. I. du Pont de Nemours and Company (US) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004014964-A2 | PHOTORESISTS, FLUORINATED POLYMERS AND PROCESSES FOR 157 nm MICROLITHOGRAPHY | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10336717-B2 | Inhibitors of beta-secretase | BACE1, BACE2, PSEN1 | ALB 4694/4885RXRA 4757/4885CES2 943/4885 |
| US-20160272600-A1 | INHIBITORS OF BETA-SECRETASE | BACE1, BACE2, PSEN1 | ALB 4694/4885RXRA 4757/4885CES2 943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.