Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 4/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27489191 | 0.88 | ABAT (0.53) | DRD2DRD3OPRM1OPRD1OPRK1 | |
| SCHEMBL27529673 | 0.85 | ENPP2 (0.49) | ENPP2DRD2OPRM1OPRD1OPRK1 | |
| SCHEMBL6882013 | 0.81 | ALDH1A1 (0.46) | DRD2DRD3OPRM1OPRD1OPRK1 | |
| SCHEMBL27502137 | 0.81 | DRD2 (0.39) | ENPP2DRD2DRD3OPRM1OPRD1 | |
| SCHEMBL6883552 | 0.80 | ESR1 (0.56) | DRD2DRD3OPRM1OPRD1OPRK1 | |
| SCHEMBL1669547 | 0.76 | HTR7 (0.56) | DRD2DRD3OPRM1OPRD1OPRK1 | |
| SCHEMBL27502902 | 0.76 | ENPP2 (0.52) | ENPP2DRD2ABATFGFR1FGFR2 | |
| SCHEMBL6875817 | 0.74 | ACHE (0.48) | ESR1NR1H2NR1H3ESR2ADRA2A | |
| SCHEMBL1026879 | 0.74 | NR1H2 (0.39) | ESR1NR1H2NR1H3HTR7LTB4R2 | |
| SCHEMBL27487451 | 0.73 | ESR1 (0.41) | DRD2DRD3OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100357258-C | Production of keto acids | CIBA SC HOLDING AG (CH) | 2007-12-26 | — | — | CN | disclosed |
| CN-1301962-C | Production of keto acids | CIBA SC HOLDING AG (CH) | 2007-02-28 | — | — | CN | disclosed |
| CN-1575274-A | Production of keto acids | CIBA SC HOLDING AG (CH) | 2005-02-02 | — | — | CN | disclosed |
| CN-1197062-A | Production of keto acids | CIBA SC HOLDING AG (CH) | 1998-10-28 | — | — | CN | disclosed |