Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.47 |
| ▸ | ITGAV | P06756 | 18/20 | 0.47 |
| ▸ | ITGB6 | P18564 | 14/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ITGB8 | P26012 | 3/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.39 |
| ▸ | ITGA8 | P53708 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27484813 | 0.88 | ITGB3 (0.47) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL27522236 | 0.87 | ITGB1 (0.41) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL7832530 | 0.85 | ITGB3 (0.64) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL27555002 | 0.84 | HTT (0.43) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL27501985 | 0.81 | ITGB1 (0.44) | ITGB3ITGAVITGB1ITGA5MEN1 | |
| SCHEMBL27484439 | 0.79 | ITGB1 (0.39) | ITGB3ITGAVITGB1ITGA5KDM4E | |
| SCHEMBL7340807 | 0.78 | ITGB3 (0.63) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL7339213 | 0.78 | MEN1 (0.46) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL7345088 | 0.77 | ITGB3 (0.41) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL6779870 | 0.77 | ITGB3 (0.45) | ITGB3ITGAVITGB6ITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1201454-A | Meta-guanidino, ureido, thioureido or azacyclic aminobenzoic acid derivatives as integrin antagonists | SEARLE & CO (US) | 1998-12-09 | — | — | CN | claimed |