Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 3/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.36 |
| ▸ | ITGAV | P06756 | 2/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27502752 | 0.91 | KMT2A (0.41) | ITGB1ITGA5KMT2APKMHTT | |
| SCHEMBL27501985 | 0.85 | ITGB1 (0.44) | ITGB1ITGA5KMT2AHTTGPR139 | |
| SCHEMBL27503083 | 0.84 | HTT (0.43) | ITGB1ITGA5KMT2APKMHTT | |
| SCHEMBL6777703 | 0.84 | ITGB3 (0.46) | ITGB1ITGA5ITGB3ITGAVMDM4 | |
| SCHEMBL27521095 | 0.82 | KMT2A (0.42) | ITGB1ITGA5KMT2AMAPK1GPR139 | |
| SCHEMBL7340359 | 0.81 | GPR139 (0.40) | ITGB1ITGA5KMT2APKMHTT | |
| SCHEMBL27522236 | 0.81 | ITGB1 (0.41) | ITGB1ITGA5KMT2AGPR139MEN1 | |
| SCHEMBL27555002 | 0.81 | HTT (0.43) | ITGB1ITGA5KMT2AHTTMAPK1 | |
| SCHEMBL27486190 | 0.80 | GPR139 (0.46) | ITGB1ITGA5KMT2APKMHTT | |
| SCHEMBL27503085 | 0.79 | ITGB3 (0.47) | ITGB1ITGA5KMT2AHTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1201454-A | Meta-guanidino, ureido, thioureido or azacyclic aminobenzoic acid derivatives as integrin antagonists | SEARLE & CO (US) | 1998-12-09 | — | — | CN | claimed |