Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.38 |
| ▸ | ITGAV | P06756 | 6/20 | 0.38 |
| ▸ | ITGB6 | P18564 | 6/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.38 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.38 |
| ▸ | ITGA8 | P53708 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27522236 | 0.90 | ITGB1 (0.41) | KDM4EITGB3ITGAVITGB6ITGB1 | |
| SCHEMBL27484813 | 0.87 | ITGB3 (0.47) | HTTLMNAKDM4EMAPTITGB3 | |
| SCHEMBL7345759 | 0.84 | ITGB3 (0.56) | HTTLMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL27503085 | 0.84 | ITGB3 (0.47) | HTTLMNAKDM4EMAPTITGB3 | |
| SCHEMBL27501985 | 0.83 | ITGB1 (0.44) | HTTSMN1; SMN2ITGB3ITGAVITGB1 | |
| SCHEMBL7345869 | 0.81 | HTT (0.43) | HTTLMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL27484439 | 0.81 | ITGB1 (0.39) | HTTKDM4ESMN1; SMN2ITGB3ITGAV | |
| SCHEMBL27521095 | 0.78 | KMT2A (0.42) | LMNAMAPTSMN1; SMN2ITGB1ITGA5 | |
| SCHEMBL27486190 | 0.78 | GPR139 (0.46) | HTTKDM4ESMN1; SMN2ITGB1ITGA5 | |
| SCHEMBL27486185 | 0.77 | ALDH1A1 (0.41) | ITGB3ITGAVITGB1ITGA5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1201454-A | Meta-guanidino, ureido, thioureido or azacyclic aminobenzoic acid derivatives as integrin antagonists | SEARLE & CO (US) | 1998-12-09 | — | — | CN | claimed |