Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 15/20 | 0.40 |
| ▸ | NOS3 | P29474 | 12/20 | 0.38 |
| ▸ | NOS2 | P35228 | 7/20 | 0.38 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902860 | 0.75 | MTNR1A (0.43) | ASIC3NOS1NOS3 | |
| SCHEMBL6619732 | 0.73 | NOS1 (0.50) | NOS1NOS3NOS2 | |
| SCHEMBL1915309 | 0.73 | ASIC3 (0.53) | ASIC3 | |
| SCHEMBL30251342 | 0.73 | ASIC3 (0.53) | ASIC3 | |
| SCHEMBL27981572 | 0.71 | NOS1 (0.38) | ASIC3NOS1NOS3NOS2 | |
| Hydrochloric Acid SCHEMBL6616517 | 0.70 | NOS1 (0.57) | ASIC3NOS1NOS3IDH1 | |
| SCHEMBL3630731 | 0.69 | GRM5 (0.37) | — | |
| SCHEMBL2711706 | 0.69 | HSD17B10 (0.55) | ASIC3NOS1NOS3NOS2 | |
| SCHEMBL3935260 | 0.69 | MPL (0.55) | ASIC3NOS1NOS3NOS2 | |
| SCHEMBL3366206 | 0.69 | ASIC3 (0.53) | ASIC3NOS1NOS3NOS2IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1546470-A | 6-phenylpyridyl-2-amine derivatives | ������ҩ������˾ | 2004-11-17 | — | — | CN | disclosed |
| CN-1168719-C | 6-phenylpyridin-2-ylamine derivatives, pharmaceutical compositions and uses | ������ҩ������˾ | 2004-09-29 | — | — | CN | disclosed |
| CN-1215391-A | 6-phenylpyridyl-2-amine derivatives | PFIZER (US) | 1999-04-28 | — | — | CN | disclosed |