Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 2/20 | 0.35 |
| ▸ | EDNRA | P25101 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GALK1 | P51570 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27517447 | 0.79 | PGR (0.39) | PGREDNRBEDNRAMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL27561373 | 0.77 | GPR3 (0.34) | — | |
| Hydrochloric Acid SCHEMBL6902647 | 0.75 | PGR (0.36) | PGREDNRBEDNRAMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL27499114 | 0.74 | PDCD1 (0.34) | EDNRBEDNRAL3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL6908519 | 0.73 | EDNRB (0.35) | PGREDNRBEDNRAMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL6909394 | 0.71 | KMO (0.34) | PGREDNRBEDNRAMEN1NPC1 | |
| SCHEMBL6902652 | 0.71 | PGR (0.38) | PGREDNRBEDNRAMEN1NPC1 | |
| SCHEMBL6908524 | 0.69 | PGR (0.37) | PGREDNRBEDNRAMEN1NPC1 | |
| SCHEMBL30719676 | 0.64 | EDNRB (0.46) | EDNRBEDNRAMEN1NPC1MAPT | |
| SCHEMBL7930011 | 0.63 | L3MBTL1 (0.47) | PGRMEN1NPC1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1229395-C | Process for producing vinyl compound polymer | SUMITOMO CHEMICAL CO (JP) | 2005-11-30 | — | — | CN | disclosed |
| CN-1386765-A | Process for producing vinyl compound polymer | SUMITOMO CHEMICAL CO (JP) | 2002-12-25 | — | — | CN | disclosed |