Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27505811 | 0.78 | MAOA (0.32) | — | |
| Hydrochloric Acid SCHEMBL1115771 | 0.76 | CYP19A1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL28994366 | 0.74 | ACHE (0.32) | ACHECHRNB2CHRNA4CYP1A2CYP2A6 | |
| SCHEMBL29049889 | 0.74 | SLC6A2 (0.35) | ACHECHRNB2CHRNA4CYP1A2CYP2A6 | |
| SCHEMBL8038491 | 0.69 | ACHE (0.31) | ACHECHRNB2CHRNA4CYP1A2CYP2A6 | |
| Hydrochloric Acid SCHEMBL7635462 | 0.69 | CHRNB2 (0.32) | ACHECHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7638377 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL6910480 | 0.68 | — | — | |
| SCHEMBL28316511 | 0.68 | ACHE (0.34) | ACHECHRNB2CHRNA4 | |
| SCHEMBL5823074 | 0.67 | GAA (0.44) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1229395-C | Process for producing vinyl compound polymer | SUMITOMO CHEMICAL CO (JP) | 2005-11-30 | — | — | CN | disclosed |
| CN-1386765-A | Process for producing vinyl compound polymer | SUMITOMO CHEMICAL CO (JP) | 2002-12-25 | — | — | CN | disclosed |