Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4450337 | 0.84 | ALDH1A1 (0.47) | FFAR1LMNAKDM4ECYP3A4FFAR4 | |
| SCHEMBL4441750 | 0.79 | LMNA (0.52) | SPHK1LMNACYP2D6GMNNPOLB | |
| SCHEMBL1133423 | 0.74 | LMNA (0.38) | GPR84SPHK1FFAR1LMNAMAPT | |
| SCHEMBL27460058 | 0.74 | LMNA (0.52) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL27843870 | 0.72 | GPR84 (0.50) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL23789287 | 0.71 | FFAR1 (0.67) | GPR84SPHK1FFAR1LMNAFFAR4 | |
| SCHEMBL22805015 | 0.71 | SPHK1 (0.68) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL22804708 | 0.71 | SPHK1 (0.68) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL22804812 | 0.71 | SPHK1 (0.68) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL22804810 | 0.71 | SPHK1 (0.68) | GPR84SPHK1FFAR1LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4838936-B2 | — | — | 2011-12-14 | — | — | JP | claimed |
| US-7591949-B2 | Method for the improvement of transport across adaptable semi-permeable barriers | IDEA AG (DE) | 2009-09-22 | — | — | US | claimed |
| US-20070184114-A1 | Formulation for topical non-invasive application in vivo | IDEA AG (DE) | 2007-08-09 | — | — | US | claimed |
| US-20050123897-A1 | Method for the improvement of transport across adaptable semi-permeable barriers | IDEA AG | 2005-06-09 | — | — | US | claimed |
| EP-1140021-B1 | IMPROVED FORMULATION FOR TOPICAL NON-INVASIVE APPLICATION IN VIVO | IDEA AG (DE) | 2004-08-04 | — | — | EP | claimed |
| US-20030099694-A1 | Method for the improvement of transport across adaptable semi-permeable barriers | IDEA AG (DE) | 2003-05-29 | — | — | US | claimed |
| JP-2002533379-A | — | — | 2002-10-08 | — | — | JP | claimed |
| US-20020064524-A1 | Formulation for topical non-invasive application in vivo | IDEA AG (DE) | 2002-05-30 | — | — | US | claimed |
| EP-1189598-A1 | A METHOD FOR THE IMPROVEMENT OF TRANSPORT ACROSS ADAPTABLE SEMI-PERMEABLE BARRIERS | IDEA AG (DE) | 2002-03-27 | — | — | EP | claimed |
| EP-1140021-A1 | IMPROVED FORMULATION FOR TOPICAL NON-INVASIVE APPLICATION IN VIVO | IDEA AG (DE) | 2001-10-10 | — | — | EP | claimed |
| WO-2001001963-A1 | A METHOD FOR THE IMPROVEMENT OF TRANSPORT ACROSS ADAPTABLE SEMI-PERMEABLE BARRIERS | IDEA AG (DE) | 2001-01-11 | — | — | WO | claimed |
| WO-2001001962-A1 | A METHOD FOR THE IMPROVEMENT OF TRANSPORT ACROSS ADAPTABLE SEMI-PERMEABLE BARRIERS | IDEA AG. (DE) | 2001-01-11 | — | — | WO | claimed |
| EP-1039880-A1 | METHOD FOR DEVELOPING, TESTING AND USING ASSOCIATES OF MACROMOLECULES AND COMPLEX AGGREGATES FOR IMPROVED PAYLOAD AND CONTROLLABLE DE/ASSOCIATION RATES | Idea Innovative Dermale Applikationen GmbH (DE) | 2000-10-04 | — | — | EP | claimed |
| WO-2000038653-A1 | IMPROVED FORMULATION FOR TOPICAL NON-INVASIVE APPLICATION IN VIVO | IDEA AG. (DE) | 2000-07-06 | — | — | WO | claimed |
| WO-2000024377-A1 | METHOD FOR DEVELOPING, TESTING AND USING ASSOCIATES OF MACROMOLECULES AND COMPLEX AGGREGATES FOR IMPROVED PAYLOAD AND CONTROLLABLE DE/ASSOCIATION RATES | IDEA INNOVATIVE DERMALE APPLIKATIONEN GMBH (DE) | 2000-05-04 | — | — | WO | claimed |
| US-20150313829-A1 | TOPICAL FORMULATIONS FOR THE PREVENTION AND TREATMENT OF ALOPECIA AND INHIBITION OF HAIR GROWTH | UNIVERSIDADE FEDERAL DE MINAS GERAIS (BR) | 2015-11-05 | — | — | US | disclosed |
| US-20150094331-A1 | QUINOLONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2015-04-02 | — | — | US | disclosed |
| WO-2000044349-A1 | NON-INVASIVE VACCINATION THROUGH THE SKIN | IDEA AG (DE) | 2000-08-03 | — | — | WO | disclosed |
| WO-2000038653-A1 | IMPROVED FORMULATION FOR TOPICAL NON-INVASIVE APPLICATION IN VIVO | IDEA AG. (DE) | 2000-07-06 | — | — | WO | disclosed |
| WO-2000024377-A1 | METHOD FOR DEVELOPING, TESTING AND USING ASSOCIATES OF MACROMOLECULES AND COMPLEX AGGREGATES FOR IMPROVED PAYLOAD AND CONTROLLABLE DE/ASSOCIATION RATES | IDEA INNOVATIVE DERMALE APPLIKATIONEN GMBH (DE) | 2000-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150094331-A1 | QUINOLONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 | PLA2G12A, PLA2G4A, PLA2G2A | GPR84 1912/4885SPHK1 1416/4885FFAR1 1020/4885 |
| US-20020064524-A1 | Formulation for topical non-invasive application in vivo | CUTA, LPO, GPX4 | GPR84 1587/4885SPHK1 1459/4885FFAR1 1101/4885 |
| US-20070184114-A1 | Formulation for topical non-invasive application in vivo | GPX4, LPO, MMP8 | GPR84 1621/4885SPHK1 1962/4885FFAR1 1511/4885 |
| US-20030099694-A1 | Method for the improvement of transport across adaptable semi-permeable barriers | ABCG2, NPC1L1, KIT | GPR84 1537/4885SPHK1 542/4885FFAR1 717/4885 |
| US-20050123897-A1 | Method for the improvement of transport across adaptable semi-permeable barriers | NPC1L1, ABCG2, SLC7A1 | GPR84 1976/4885SPHK1 836/4885FFAR1 638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.