Water

Water

SCHEMBL27522752

CO[SiH](C)OC.O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39995 0.95
SCHEMBL28205893 0.90
Fluoride SCHEMBL27524549 0.90
Methane SCHEMBL29042620 0.90
SCHEMBL3909902 0.90
SCHEMBL30672226 0.90
Ethane SCHEMBL29042623 0.90
Hydrochloric Acid SCHEMBL27635995 0.90
Ethylene SCHEMBL27532163 0.86
Fluoromethane SCHEMBL27728763 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107012456-B Modified metal surface pretreating reagent of a kind of alkoxyl silicone ethyl Polyhedral Oligomeric silsesquioxane and preparation method thereof, application 武汉大学 2019-06-28 CN disclosed
CN-109810669-A A kind of poly- silicone resin and its preparation method and application 广州市高士实业有限公司 2019-05-28 CN disclosed
CN-103869613-A Colored hardening composite, pattern hardeninig colored layer using same, colored filter and liquid crystal display device SUMITOMO CHEMICAL CO 2014-06-18 CN disclosed
CN-101598897-B Colored curable composition, pattern-cured colored layer using same, color filter, and liquid crystal display device SUMITOMO CHEMICAL CO 2014-05-14 CN disclosed
CN-101376977-B Electrogalvanized and chromate-free chemical conversion treated steel plate with excellent white rust resistant performance KOBE STEEL LTD 2011-01-19 CN disclosed
CN-101598897-A colored curable composition SUMITOMO CHEMICAL CO (JP) 2009-12-09 CN disclosed
CN-101544081-A Resin-coated metal plate with excellent film peelability in the roll forming process KOBE STEEL LTD 2009-09-30 CN disclosed
CN-100501945-C Organic thin film transistor element and method for manufacturing the same KONICA MINOLTA HOLDINGS INC (JP) 2009-06-17 CN disclosed
CN-101395215-A Aqueous resin composition TOHO CHEM IND CO LTD (JP) 2009-03-25 CN disclosed
CN-101376977-A Electrogalvanized and chromate-free chemical conversion treated steel plate with excellent white rust resistant performance KOBE STEEL LTD (JP) 2009-03-04 CN disclosed
CN-1952779-A Colored photosensitive resin composition SUMITOMO CHEMICAL CO (JP) 2007-04-25 CN disclosed
CN-1280326-C Rapid-cure, one-component mixtures, which contain alkoxysilane-terminated polymers CONSORTIUM ELEKTROCHEM IND (DE) 2006-10-18 CN disclosed
CN-1276273-C Optical element with anti-resist-film HOYA CORP (JP) 2006-09-20 CN disclosed
CN-1751385-A Organic thin film transistor element and method for manufacturing the same KONICA MINOLTA HOLDINGS INC (JP) 2006-03-22 CN disclosed
CN-1703761-A Fluorine-containing polymer solid electrolyte containing fluorine-containing ether chain DAIKIN IND LTD (JP) 2005-11-30 CN disclosed
CN-1639219-A One-component mixture containing a rapidly curing alkoxysilane-terminated polymer CONSORTIUM ELEKTROCHEM IND (DE) 2005-07-13 CN disclosed
CN-1196945-C Method for preparing coating composition for spectacles lens HOYA CORP (JP) 2005-04-13 CN disclosed
CN-1543678-A Functional device and production method therefor ���ṫ˾ 2004-11-03 CN disclosed
CN-1414398-A Optical element with anti-resist-film HOYA CORP (JP) 2003-04-30 CN disclosed
CN-1346987-A Method for preparing coating composition for spectacles lens HOYA CORP (JP) 2002-05-01 CN disclosed