Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | PEPD | P12955 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438712 | 0.82 | ADRB2 (0.40) | PRMT1F2PRSS1PRSS3MAPT | |
| SCHEMBL18028464 | 0.81 | KIF11 (0.54) | PRMT1KIF11GLACYP17A1NAMPT | |
| SCHEMBL15149335 | 0.80 | MIF (0.48) | MAPT | |
| SCHEMBL617014 | 0.80 | MAPT (0.52) | ALDH1A1MAPT | |
| SCHEMBL8898242 | 0.79 | F7 (0.45) | F2ALDH1A1 | |
| SCHEMBL32687527 | 0.79 | RAB9A (0.49) | ALDH1A1NPC1MAPT | |
| SCHEMBL616504 | 0.79 | CA1 (0.46) | GLAALDH1A1GAAMAPT | |
| SCHEMBL7422422 | 0.79 | NFKB1 (0.39) | CYP17A1NAMPTMAPT | |
| SCHEMBL7158402 | 0.79 | PPARG (0.47) | ALDH1A1NPC1GAA | |
| SCHEMBL5731734 | 0.78 | LOXL2 (0.49) | NAMPTPRSS1ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1208314-C | Factor VIIA inhibitor (thio) urea derivatives, their preparation and their use | AVENTIS PHARMA GMBH (DE) | 2005-06-29 | — | — | CN | disclosed |
| CN-1427818-A | Factor VIIA inhibitor (thio) urea derivatives, their preparation and their use | AVENTIS PHARMA GMBH (DE) | 2003-07-02 | — | — | CN | disclosed |