Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ESR1 | P03372 | 3/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360886 | 0.80 | KMT2A (0.75) | MEN1KMT2AESR1ESR2GAA | |
| SCHEMBL28744253 | 0.80 | MEN1 (0.41) | MEN1KMT2AESR1ESR2GAA | |
| SCHEMBL5372781 | 0.78 | MEN1 (0.48) | MEN1KMT2AESR1ESR2GAA | |
| SCHEMBL28741143 | 0.77 | MEN1 (0.47) | MEN1KMT2AESR1ESR2GAA | |
| SCHEMBL5366223 | 0.75 | HSD11B1 (0.55) | MEN1KMT2AESR1ESR2GAA | |
| SCHEMBL19125575 | 0.74 | KMT2A (0.50) | MEN1KMT2AESR1ESR2GAA | |
| SCHEMBL3480009 | 0.72 | ALDH1A1 (0.54) | MEN1KMT2AESR1ESR2GAA | |
| SCHEMBL5360980 | 0.72 | GAA (0.55) | MEN1KMT2AESR1ESR2GAA | |
| SCHEMBL13605945 | 0.70 | KMT2A (0.64) | MEN1KMT2AESR1ESR2GAA | |
| SCHEMBL6058028 | 0.70 | KMT2A (0.52) | MEN1KMT2AESR1ESR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1237961-A | Aminoguanidines and alkoxyguanidines as protease inhibitors | DIMENSIONAL PHARM INC (US) | 1999-12-08 | — | — | CN | disclosed |