SCHEMBL5360980

SCHEMBL5360980

COc1ccc(S(=O)(=O)Oc2cccc(O)c2O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.55
KMT2A Q03164 2/20 0.55
MEN1 O00255 1/20 0.55
ESR1 P03372 1/20 0.55
ESR2 Q92731 1/20 0.55
HSD11B1 P28845 1/20 0.52
HSD17B3 P37058 1/20 0.52
LMNA P02545 3/20 0.51
HTT P42858 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
ALDH1A1 P00352 2/20 0.50
KDM4E B2RXH2 1/20 0.50
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50
ALOX12 P18054 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8054575 0.84 TUBB4A (0.57) GAAKMT2AMEN1ESR1ESR2
SCHEMBL5360886 0.84 KMT2A (0.75) GAAKMT2AMEN1ESR1ESR2
SCHEMBL2881876 0.82 TUBB4A (0.63) GAAKMT2AMEN1ESR1ESR2
SCHEMBL5366223 0.82 HSD11B1 (0.55) GAAKMT2AMEN1ESR1ESR2
Pyrogallol SCHEMBL2881879 0.79 PKM (0.51) GAALMNASMN1; SMN2L3MBTL1ALDH1A1
Pyrogallol SCHEMBL5360986 0.79 PKM (0.51) GAALMNASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL8818918 0.78 LMNA (0.58) GAALMNAHTTSMN1; SMN2TDP1
SCHEMBL11775991 0.76 MAPT (0.47) KMT2ALMNAHTTSMN1; SMN2TDP1
SCHEMBL8818892 0.75 TDP1 (0.68) GAAKMT2AMEN1LMNAHTT
SCHEMBL9308804 0.75 TDP1 (0.73) GAAKMT2ALMNAHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7179399-B2 Material for forming protective film TOKYO OHKA KOGYO CO., LTD. (JP) 2007-02-20 US disclosed
US-6693049-B2 FILLING WITH AN OXYALKYLATED MELAMINE, BENZOGUANAMINE, ACETOGUANAMINE, GLYCOL URYL, UREA, THIOUREA, GUANIDINE, ALKYLENEUREA OR SUCCINYLAMIDE AND HEATING AT 150-250 C, WHEREBY NO BUBBLE IS GENERATED WHEN THE FINE HOLE IS FILLED. TOKYO OHKA KOGYO CO., LTD. (JP) 2004-02-17 US disclosed
US-20030032280-A1 Method for filling fine hole TOKYO OHKA KOGYO CO., LTD. (JP) 2003-02-13 US disclosed
US-20020182360-A1 Material for forming protective film TOKYO OHKA KOGYO CO., LTD. (JP) 2002-12-05 US disclosed
EP-0749044-B1 Positive-working photoresist composition TOKYO OHKA KOGYO CO LTD (JP) 2000-09-06 EP disclosed
EP-0749046-B1 Positive-working photoresist composition TOKYO OHKA KOGYO CO LTD (JP) 2000-05-10 EP disclosed
US-5948589-A HIGH SENSITIVITY AND HIGH RESOLUTION CAPABLE OF EXHIBITING HIGH STABILITY OF LATENT IMAGES; TERT-BUTYOXYCARBONYL-SUBSTITUTED POLYVINYLPHENOL AND ALKOXYALKYL-SUBSTITUTED POLYVINYLPHENOL. TOKYO OHKA KOGYO CO., LTD. (JP) 1999-09-07 US disclosed
US-5874195-A Positive-working photoresist composition TOKYO OHKA KOGYO CO., LTD. (JP) 1999-02-23 US disclosed
US-5856058-A HALATION INHIBITOR WHICH IS AN ESTERIFICATION PRODUCT BETWEEN A SPECIFIED PHENOLIC COMPOUND AND A NAPHTHOQUINONE-1,2-DIAZIDE SULFONIC ACID. TOKYO OHKA KOGYO CO., LTD. (JP) 1999-01-05 US disclosed
US-5770343-A Positive-working photoresist composition TOKYO OHKA KOGYO CO., LTD. (JP) 1998-06-23 US disclosed
EP-0749044-A2 Positive-working photoresist composition TOKYO OHKA KOGYO CO., LTD. (JP) 1996-12-18 EP disclosed
EP-0749046-A1 Positive-working photoresist composition TOKYO OHKA KOGYO CO., LTD. (JP) 1996-12-18 EP disclosed