Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | STS | P08842 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | CDC25B | P30305 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | LIG1 | P18858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6616664 | 0.86 | MAPT (0.69) | MAPTLMNARAB9AKMT2AALDH1A1 | |
| Benzophenone SCHEMBL11416830 | 0.84 | MAPT (0.67) | MAPTLMNARAB9AALDH1A1KDM4E | |
| SCHEMBL50229 | 0.82 | MAPT (0.64) | MAPTLMNARAB9AALDH1A1KDM4E | |
| SCHEMBL29573531 | 0.82 | MAPT (0.64) | MAPTLMNARAB9AALDH1A1KDM4E | |
| SCHEMBL29039855 | 0.81 | LMNA (0.63) | MAPTLMNARAB9AKMT2AMEN1 | |
| SCHEMBL27507752 | 0.81 | MAPT (0.56) | MAPTLMNARAB9AKMT2AMEN1 | |
| SCHEMBL8439039 | 0.81 | ALDH1A1 (0.64) | MAPTLMNARAB9AALDH1A1KDM4E | |
| Bicarbonate SCHEMBL27740092 | 0.81 | MAPT (0.62) | MAPTLMNARAB9AALDH1A1KDM4E | |
| SCHEMBL7929339 | 0.80 | MAPT (0.91) | MAPTLMNARAB9AKMT2AMEN1 | |
| SCHEMBL3484026 | 0.79 | RAB9A (0.66) | MAPTLMNARAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1272884-A | Adipocyte-specific protein homologs | ZYMOGENETICS INC (US) | 2000-11-08 | — | — | CN | disclosed |
| CN-1263882-A | Method for preparing fluorine-substituted aromatic compound | MITSUI CHEMICALS INC (JP) | 2000-08-23 | — | — | CN | disclosed |