Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21808286 | 0.85 | TRPV4 (0.43) | — | |
| SCHEMBL21815522 | 0.85 | EGLN2 (0.41) | ALDH1A1LMNAHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL7229570 | 0.76 | NOTUM (0.44) | ALDH1A1XDH | |
| SCHEMBL2753937 | 0.72 | ALDH1A1 (0.42) | ALDH1A1LMNAHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL2750812 | 0.72 | KDM4E (0.32) | ALDH1A1 | |
| SCHEMBL2753286 | 0.72 | DRD2 (0.33) | — | |
| SCHEMBL2751136 | 0.70 | NOTUM (0.30) | — | |
| SCHEMBL2751641 | 0.70 | NOTUM (0.49) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2751393 | 0.70 | NOTUM (0.42) | ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL2752143 | 0.70 | RXRA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178540-B2 | Pyrimidylmethyl-sulfonamide compounds | BASF SE (DE) | 2012-05-15 | — | — | US | disclosed |
| US-20100077512-A1 | Pyridazin-4-ylmethyl-sulfonamides used as Fungicides and Against Arthropods | BASF SE (DE) | 2010-03-25 | — | — | US | disclosed |
| US-20100069243-A1 | Pyrimidylmethyl-Sulfonamide Compounds | BASF SE (DE) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069243-A1 | Pyrimidylmethyl-Sulfonamide Compounds | TPMT, NISCH, PPA1 | ALDH1A1 1588/4885LMNA 4514/4885HPGD 1849/4885 |
| US-20100077512-A1 | Pyridazin-4-ylmethyl-sulfonamides used as Fungicides and Against Arthropods | PIR, PRDX4, PRDX2 | ALDH1A1 2607/4885LMNA 3316/4885HPGD 3485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.