Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.52 |
| ▸ | KDM5A | P29375 | 9/20 | 0.52 |
| ▸ | KDM5B | Q9UGL1 | 9/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.47 |
| ▸ | KDM5C | P41229 | 5/20 | 0.47 |
| ▸ | KDM4A | O75164 | 4/20 | 0.47 |
| ▸ | KDM4B | O94953 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KDM6B | O15054 | 2/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.46 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.46 |
| ▸ | TET3 | O43151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27925527 | 0.81 | KDM4C (0.62) | KDM4CKDM5AKDM5BKDM2BKDM5C | |
| SCHEMBL9519602 | 0.80 | ALKBH2 (0.53) | ALKBH5FTO | |
| SCHEMBL27542831 | 0.80 | KDM4C (0.63) | KDM4CKDM5AKDM5BKDM2BKDM5C | |
| SCHEMBL9517034 | 0.79 | LNPEP (0.44) | KDM4CKDM5AKDM5BNR4A2MEN1 | |
| SCHEMBL27683139 | 0.79 | RXRA (0.52) | NR4A2NR4A1NR4A3EGLN1CYSLTR1 | |
| SCHEMBL837794 | 0.78 | NR4A2 (0.58) | KDM4CKDM5AKDM5BNR4A2MEN1 | |
| Hydrochloric Acid SCHEMBL30523486 | 0.78 | KDM4C (0.61) | KDM4CKDM5AKDM5BKDM2BKDM5C | |
| SCHEMBL5567317 | 0.78 | ALDH1A1 (0.55) | KDM4CKDM5AKDM5BNR4A2KDM2B | |
| SCHEMBL5566899 | 0.78 | KDM4C (0.47) | KDM4CKDM5AKDM5BKDM2BKDM5C | |
| SCHEMBL17820831 | 0.78 | KDM4C (0.53) | KDM4CKDM5AKDM5BKDM2BKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1079466-A | 4-or 5-(sulphur) acylimino-and (inferior sulphur) amidopyridine and pyridine-N-oxide thereof | HOECHST AG (DE) | 1993-12-15 | — | — | CN | disclosed |
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |