Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.33 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27501269 | 0.82 | ALDH1A1 (0.37) | LMNAALDH1A1 | |
| SCHEMBL2585956 | 0.80 | CALM1 (0.43) | LTA4HCALM1 | |
| SCHEMBL9686662 | 0.79 | SRD5A2 (0.38) | IDO1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL27430888 | 0.79 | TP53 (0.44) | LMNAALDH1A1L3MBTL1LTA4HCALM1 | |
| SCHEMBL8900207 | 0.79 | SIGMAR1 (0.37) | IDO1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL711973 | 0.78 | CALM1 (0.57) | IDO1LMNAALDH1A1LTA4HCALM1 | |
| SCHEMBL4841473 | 0.78 | CALM1 (0.57) | IDO1HTR1DHTR1BCNR2LMNA | |
| SCHEMBL27427349 | 0.78 | LTA4H (0.35) | LTA4HCALM1 | |
| SCHEMBL3956146 | 0.78 | IDO1 (0.56) | IDO1HTR1DHTR1BMEN1KMT2A | |
| SCHEMBL27454348 | 0.76 | MAPT (0.46) | MEN1KMT2ALMNAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1110484-C | 2-(arylphenyl) amino-imidazoline derivatives | HOFMMANN LA ROCHE AG F (CH) | 2003-06-04 | — | — | CN | disclosed |
| CN-1216762-A | 2-(arylphenyl) amino-imidazoline derivatives | HOFMMANN LA ROCHE AG F (CH) | 1999-05-19 | — | — | CN | disclosed |