Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19383618 | 1.00 | AGTR1 (0.50) | AGTR1CYP1A1CYP1A2CYP1B1MEN1 | |
| SCHEMBL14416408 | 0.94 | CYP1B1 (0.50) | AGTR1CYP1A1CYP1A2CYP1B1MEN1 | |
| SCHEMBL15502106 | 0.93 | AGTR1 (0.49) | AGTR1CYP1A1CYP1A2CYP1B1MEN1 | |
| SCHEMBL19383283 | 0.91 | AGTR1 (0.45) | AGTR1CYP1A1CYP1A2CYP1B1MEN1 | |
| SCHEMBL10051210 | 0.91 | MEN1 (0.54) | CYP1A2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL12306181 | 0.91 | MEN1 (0.54) | CYP1A2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10051196 | 0.91 | MEN1 (0.54) | CYP1A2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10051293 | 0.91 | MEN1 (0.54) | CYP1A2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14725231 | 0.91 | MAPT (0.54) | CYP1A2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL17969997 | 0.89 | MEN1 (0.53) | MEN1KMT2AALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190106391-A1 | COMPOUNDS WITH SPIROBIFLUORENE-STRUCTURES | MERCK PATENT GMBH (DE) | 2019-04-11 | — | — | US | disclosed |
| WO-2017157983-A1 | COMPOUNDS WITH SPIROBIFLUORENE-STRUCTURES | MERCK PATENT GMBH (DE) | 2017-09-21 | — | — | WO | disclosed |
| US-9523031-B2 | Organic electroluminescent device | IDEMITSU KOSAN CO., LTD. (JP) | 2016-12-20 | — | — | US | disclosed |
| US-9523031-B2 | Organic electroluminescent device | IDEMITSU KOSAN CO., LTD. (JP) | 2016-12-20 | — | — | US | disclosed |
| US-20140018536-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2014-01-16 | — | — | US | disclosed |
| US-20140018536-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2014-01-16 | — | — | US | disclosed |
| US-8586206-B2 | Aromatic amine derivative and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2013-11-19 | — | — | US | disclosed |
| EP-2589596-A1 | AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | Idemitsu Kosan Co., Ltd. (JP) | 2013-05-08 | — | — | EP | disclosed |
| US-20120001154-A1 | Aromatic amine derivative and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. | 2012-01-05 | — | — | US | disclosed |
| US-20120001154-A1 | Aromatic amine derivative and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. | 2012-01-05 | — | — | US | disclosed |
| US-20070224448-A1 | Organic Electroluminescent Device | IDEMITSU KOSAN CO., LTD. (JP) | 2007-09-27 | — | — | US | disclosed |
| US-20070224448-A1 | Organic Electroluminescent Device | IDEMITSU KOSAN CO., LTD. (JP) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190106391-A1 | COMPOUNDS WITH SPIROBIFLUORENE-STRUCTURES | TEC, NUDT1, DPYD | AGTR1 788/4885CYP1A1 1403/4885CYP1A2 711/4885 |
| US-20120001154-A1 | Aromatic amine derivative and organic electroluminescence device using the same | AOC3, NPR3, AOC2 | AGTR1 951/4885CYP1A1 495/4885CYP1A2 684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.