Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of 2-Mercaptopyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Mercaptopyridine SCHEMBL27535511 | 0.97 | — | — | |
| 2-Mercaptopyridine SCHEMBL8709490 | 0.97 | KDM4E (0.48) | — | |
| 2-Mercaptopyridine SCHEMBL11748206 | 0.97 | KDM4E (0.48) | — | |
| 2-Mercaptopyridine SCHEMBL29429262 | 0.97 | — | — | |
| 2-Mercaptopyridine SCHEMBL2058513 | 0.97 | — | — | |
| 2-Mercaptopyridine SCHEMBL27748087 | 0.94 | — | — | |
| 2-Mercaptopyridine SCHEMBL27521882 | 0.94 | — | — | |
| 2-Mercaptopyridine SCHEMBL28194263 | 0.94 | — | — | |
| 2-Mercaptopyridine SCHEMBL28776936 | 0.94 | — | — | |
| 2-Mercaptopyridine SCHEMBL27548172 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101460060-A | Compositions and methods for topical treatment of tar-responsive skin disorders | TRISTRATA INC (US) | 2009-06-17 | — | — | CN | claimed |
| CN-104116646-B | Concentrated type personal cleaning compositions | 宝洁公司 | 2018-08-17 | — | — | CN | disclosed |
| CN-104159640-B | Personal care compositions comprising end-functionalized ionic silicones | 莫门蒂夫性能材料股份有限公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-107080701-A | Personal cleansing cleaning agent | 荷兰联合利华有限公司 | 2017-08-22 | — | — | CN | disclosed |
| CN-101442908-B | The tick of preparation and insect repellent composition | 纳幕尔杜邦公司 | 2016-09-28 | — | — | CN | disclosed |
| CN-102510723-B | Comprise the disinfectant of eugenol, terpinol and thymol | 荷兰联合利华有限公司 | 2016-08-10 | — | — | CN | disclosed |
| CN-102743301-B | The cosmetic composition that comprises ampholyte copolymer | RHONE POULENC CHIMIE (FR) | 2016-05-04 | — | — | CN | disclosed |
| CN-102361894-B | Based on acrylamido-, methacrylamido-or ethyl propylene amidoalkyl sulfonic acid or-alkylsulfonate and carboxyalkyl-acrylate ,-methacrylic ester or-ethyl propylene acid esters or these carboxylic compounds the polymkeric substance of oligopolymer | CLARIANT FINANCE (BVI) LTD. (VG) | 2015-08-26 | — | — | CN | disclosed |
| CN-104159640-A | Personal care compositions comprising end-functionalized ionic silicones | MOMENTIVE PERFORMANCE MAT INC | 2014-11-19 | — | — | CN | disclosed |
| CN-101247785-B | Cosmetic composition containing an amholyte copolymer | RHONE POULENC CHIMIE | 2013-04-24 | — | — | CN | disclosed |
| CN-1809363-A | Sprayable compositions comprising pharmaceutical active agents, volatile silicones and a non-volatile oily phase | GALDERMA RES & DEV (FR) | 2006-07-26 | — | — | CN | disclosed |
| CN-1784478-A | Silyl esters, their use in binder systems and coating compositions and process for their production | SIGMAKALON B V (NL) | 2006-06-07 | — | — | CN | disclosed |
| CN-1758895-A | Use of zinc-containing layered materials to increase pyrithione activity or polyvalent metal salt activity of pyrithione | PROCTER & GAMBLE (US) | 2006-04-12 | — | — | CN | disclosed |
| CN-1758893-A | Composition comprising particulate zinc material having defined crystallite size | PROCTER & GAMBLE (US) | 2006-04-12 | — | — | CN | disclosed |
| CN-1758896-A | Composition comprising zinc-containing layered material having relatively high zinc lability | PROCTER & GAMBLE (US) | 2006-04-12 | — | — | CN | disclosed |
| CN-1642522-A | Uv absorber compositions comprising a hydroxyphenyltriazine compound | CIBA SC HOLDING AG (CH) | 2005-07-20 | — | — | CN | disclosed |
| CN-1617700-A | Cosmetic or personal care composition | UNILEVER NV (NL) | 2005-05-18 | — | — | CN | disclosed |
| CN-1455661-A | Novel cosmetic, personal care, detergent and nutritional supplement compositions containing bioactive glass and methods of making and using the same | SCHOTT GLAS (DE) | 2003-11-12 | — | — | CN | disclosed |
| CN-1436520-A | Antiscurf and antiitch composition containing sensory agent and sensory intensifier compound | INT FLAVORS & FRAGRANCES INC (US) | 2003-08-20 | — | — | CN | disclosed |
| CN-1388232-A | Detergent composition | KAO CORP (JP) | 2003-01-01 | — | — | CN | disclosed |