Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.55 |
| ▸ | HRH1 | P35367 | 6/20 | 0.54 |
| ▸ | HTR2A | P28223 | 5/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766257 | 0.94 | SIGMAR1 (0.58) | SIGMAR1HRH1HTR2AMTNR1AMTNR1B | |
| SCHEMBL28048962 | 0.85 | RIPK1 (0.55) | LMNA | |
| SCHEMBL8494372 | 0.78 | HRH1 (0.54) | SIGMAR1HRH1HTR2AMTNR1AMTNR1B | |
| SCHEMBL18761314 | 0.78 | HRH1 (0.54) | SIGMAR1HRH1HTR2AMTNR1AMTNR1B | |
| SCHEMBL5692956 | 0.78 | TBXAS1 (0.63) | HRH1HTR2AMTNR1AMTNR1BEPHX2 | |
| SCHEMBL9073997 | 0.78 | HRH1 (0.71) | SIGMAR1HRH1HTR2ACHRM2HTR1A | |
| SCHEMBL4219820 | 0.77 | HRH1 (0.57) | HRH1HTR2AMTNR1AMTNR1BEPHX2 | |
| Hydrochloric Acid SCHEMBL2861647 | 0.77 | TBXAS1 (0.61) | HRH1HTR2AMTNR1AMTNR1BEPHX2 | |
| SCHEMBL27593431 | 0.76 | SIGMAR1 (0.49) | SIGMAR1HRH1HTR2AMTNR1AMTNR1B | |
| SCHEMBL18761347 | 0.75 | HRH1 (0.55) | SIGMAR1HRH1HTR2ATBXAS1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1336930-A | Bridged heterocyclic derivatives | GPINIL HOLDING CORP (US) | 2002-02-20 | — | — | CN | disclosed |