Sugi Predict

Sugi Predict / Compounds / SCHEMBL27555232

SCHEMBL27555232

SCHEMBL27555232

CS(=O)(=O)N(Cc1ccccc1)c1cc(C(O)CCl)ccc1Br

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ MEN1 O00255 4/20 0.35
▸ KMT2A Q03164 4/20 0.35
▸ LMNA P02545 1/20 0.35
▸ ACLY P53396 1/20 0.35
▸ ADRB3 P13945 1/20 0.35
▸ CNR2 P34972 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7529497 1.00 ALDH1A1 (0.40) ALDH1A1L3MBTL1MEN1KMT2ALMNA
SCHEMBL7530966 0.87 MEN1 (0.46) ALDH1A1L3MBTL1MEN1KMT2ALMNA
SCHEMBL7533145 0.87 MEN1 (0.46) ALDH1A1L3MBTL1MEN1KMT2ALMNA
SCHEMBL7619273 0.84 ALDH1A1 (0.39) ALDH1A1L3MBTL1MEN1KMT2ALMNA
SCHEMBL7536470 0.84 ALDH1A1 (0.39) ALDH1A1L3MBTL1MEN1KMT2ALMNA
SCHEMBL7613358 0.84 ALDH1A1 (0.39) ALDH1A1L3MBTL1MEN1KMT2ALMNA
SCHEMBL27575446 0.83 ADRB3 (0.46) ALDH1A1L3MBTL1ADRB3
SCHEMBL7536141 0.82 L3MBTL1 (0.44) ALDH1A1L3MBTL1ACLY
SCHEMBL7532766 0.82 L3MBTL1 (0.44) ALDH1A1L3MBTL1ACLY
SCHEMBL7251978 0.80 LMNA (0.50) ALDH1A1MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1360574-A Process for preparing tricyclic amino alcohol derivatives ASAHI CHEMICAL IND (JP) 2002-07-24 — — CN disclosed