Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ICMT | O60725 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27495319 | 0.83 | KDM4E (0.42) | HTTALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL27509545 | 0.79 | MPO (0.38) | SLC6A4HTR2C | |
| SCHEMBL27511350 | 0.79 | TDO2 (0.37) | HTR2C | |
| SCHEMBL27510621 | 0.77 | ITGB3 (0.48) | ALDH1A1KDM4ECYP2D6ADRA2CNPC1 | |
| SCHEMBL27532210 | 0.74 | SNCA (0.41) | ALDH1A1SLC6A4DRD2DRD3 | |
| SCHEMBL27495318 | 0.74 | GUSB (0.39) | ALDH1A1SLC6A4DRD2DRD3 | |
| SCHEMBL27510617 | 0.72 | HASPIN (0.46) | HTTALDH1A1KDM4ECYP2D6CYP1A2 | |
| SCHEMBL31616409 | 0.68 | LTC4S (0.57) | HTTALDH1A1KDM4ETDP1MTOR | |
| SCHEMBL31616374 | 0.68 | LTC4S (0.57) | HTTALDH1A1KDM4ETDP1MTOR | |
| SCHEMBL31616380 | 0.68 | LTC4S (0.57) | HTTALDH1A1KDM4ETDP1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1223650-A | Piperidines and pyrrolidines | MERCK PATENT GMBH (DE) | 1999-07-21 | — | — | CN | disclosed |