Sugi Predict

Sugi Predict / Compounds / SCHEMBL2755820

SCHEMBL2755820

SCHEMBL2755820

CNc1cc(C)ccc1OC

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ACHE P22303 1/20 0.58
▸ MAPT P10636 4/20 0.54
▸ GAA P10253 4/20 0.54
▸ TSHR P16473 4/20 0.54
▸ MAPK1 P28482 3/20 0.54
▸ LMNA P02545 3/20 0.54
▸ L3MBTL1 Q9Y468 3/20 0.54
▸ TDP1 Q9NUW8 2/20 0.54
▸ APP P05067 2/20 0.53
▸ ALDH1A1 P00352 4/20 0.52
▸ CYP3A4 P08684 1/20 0.52
▸ KMT2A Q03164 7/20 0.50
▸ MEN1 O00255 4/20 0.50
▸ POLB P06746 2/20 0.50
▸ KDM4E B2RXH2 1/20 0.50
▸ CRHBP P24387 1/20 0.50
▸ CRHR2 Q13324 1/20 0.50
▸ SMN1; SMN2 Q16637 3/20 0.49
▸ CASP3 P42574 1/20 0.49
▸ SENP7 Q9BQF6 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31239085 1.00 ACHE (0.58) ACHEMAPTGAATSHRMAPK1
SCHEMBL2755832 0.83 ACHE (0.58) ACHEMAPK1LMNAAPPALDH1A1
SCHEMBL3973574 0.81 ACHE (0.56) ACHEMAPTGAATSHRMAPK1
SCHEMBL21268606 0.81 ACHE (0.56) ACHEMAPTGAATSHRMAPK1
SCHEMBL20427585 0.81 ACHE (0.40) ACHEMAPTGAATSHRMAPK1
SCHEMBL23033431 0.78 APP (0.53) ACHEMAPTGAATSHRMAPK1
SCHEMBL1576523 0.78 GAA (0.59) MAPTGAALMNAL3MBTL1APP
SCHEMBL21965771 0.78 ACHE (0.52) ACHEMAPTGAATSHRMAPK1
SCHEMBL21564965 0.78 ACHE (0.52) ACHEMAPTGAATSHRMAPK1
SCHEMBL4387302 0.78 MAPT (0.63) ACHEMAPTGAATSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59170003-A — — None — — JP disclosed
EP-3743430-B1 AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2023-08-02 — — EP disclosed
US-20230203007-A1 PYRIDINYLACETAMIDE DERIVATIVES AS SODIUM CHANNEL ACTIVATORS X-CHEM GLOBAL HQ 2023-06-29 — — US disclosed
EP-1887008-B1 THIENOTRIAZOLODIAZEPINE COMPOUND AND A MEDICINAL USE THEREOF MITSUBISHI TANABE PHARMA CORP (JP) 2021-04-21 — — EP disclosed
US-20190135835-A1 MK2 INHIBITORS AND USES THEREOF BRISTOL-MYERS SQUIBB COMPANY 2019-05-09 — — US disclosed
US-20170208809-A1 Compositions for Inhibition of Insect Sensing VANDERBILT UNIVERSITY 2017-07-27 — — US disclosed
US-9578881-B2 Compositions for inhibition of insect sensing VANDERBILT UNIVERSITY (US) 2017-02-28 — — US disclosed
US-20140242135-A1 COMPOSITIONS FOR INHIBITION OF INSECT SENSING VANDERBILT UNIVERSITY (US) 2014-08-28 — — US disclosed
US-8383813-B2 Fused pyrrolocarbazoles CEPHALON, INC. (US) 2013-02-26 — — US disclosed
US-20120004253-A1 Novel Fused Pyrrolocarbazoles CEPHALON, INC. (US) 2012-01-05 — — US disclosed
US-4307015-A DISPERSE DYES SANDOZ LTD. (CH) 1981-12-22 — — US disclosed
EP-0021105-A1 Reactive dyes, process for their preparation and their use for dyeing cellulose fibers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-01-07 — — EP disclosed
US-4172944-A Water insoluble styryl dyestuffs having hetero-aryl methylene substituent BAYER AKTIENGESELLSCHAFT (DE) 1979-10-30 — — US disclosed
US-4129736-A FIBER-REACTIVE CIBA-GEIGY CORPORATION (US) 1978-12-12 — — US disclosed
US-4082739-A FIBRE-REACTIVE DYESTUFF CONTAINING A BIS-TRIAZINYLAMINO CIBA-GEIGY AG (CH) 1978-04-04 — — US disclosed
US-4079051-A 4-Halogeno-s-triazin-2-yl-phosphoramide acid containing reactive dyestuffs CIBA-GEIGY CORPORATION (US) 1978-03-14 — — US disclosed
US-4046771-A GREENISH-YELLOW SHADES ON SYNTHETIC FIBERS BAYER AKTIENGESELLSCHAFT (DT) 1977-09-06 — — US disclosed
US-4033944-A Fibre-reactive hydroxycycloalkenyl-halo triazinyl containing dyestuffs CIBA-GEIGY CORPORATION (US) 1977-07-05 — — US disclosed
US-4016191-A WATER INSOLUBLE; LIGHTFASTNESS BAYER AKTIENGESELLSCHAFT (DT) 1977-04-05 — — US disclosed
US-3947407-A ANTHRAQUINONE DYE CIBA-GEIGY AG (CH) 1976-03-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004253-A1 Novel Fused Pyrrolocarbazoles PC, PYCR1, CYP11B2 ACHE 1666/4885MAPT 671/4885GAA 324/4885
US-20140242135-A1 COMPOSITIONS FOR INHIBITION OF INSECT SENSING OR51E2, TRPA1, OR10J3 ACHE 152/4885MAPT 1681/4885GAA 4268/4885
US-20230203007-A1 PYRIDINYLACETAMIDE DERIVATIVES AS SODIUM CHANNEL ACTIVATORS SCN1A, SCN3A, SCN2A ACHE 439/4885MAPT 236/4885GAA 4127/4885
US-20170208809-A1 Compositions for Inhibition of Insect Sensing OR51E2, TRPA1, OR10J3 ACHE 167/4885MAPT 2002/4885GAA 4308/4885
US-20190135835-A1 MK2 INHIBITORS AND USES THEREOF MKNK2, DUSP2, MKNK1 ACHE 2851/4885MAPT 2354/4885GAA 2587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.