Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25189530 | 0.92 | ALDH1A1 (0.57) | ALDH1A1KDM4EHTTHDAC1HDAC6 | |
| SCHEMBL9242992 | 0.85 | ALDH1A1 (0.61) | ALDH1A1KDM4EHTTHDAC1HDAC6 | |
| SCHEMBL11533429 | 0.83 | CYP2C9 (0.65) | ALDH1A1HTTHDAC1HDAC6MEN1 | |
| SCHEMBL626772 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KDM4EHTTHDAC1HDAC6 | |
| SCHEMBL21091969 | 0.81 | ALDH1A1 (0.88) | ALDH1A1KDM4EHTTHDAC1HDAC6 | |
| SCHEMBL23754981 | 0.81 | LSS (0.56) | ALDH1A1KDM4EHTTHDAC6HDAC3 | |
| SCHEMBL9911471 | 0.80 | ERCC1 (0.57) | ALDH1A1KDM4EHTTHDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL28938255 | 0.80 | ALDH1A1 (0.85) | ALDH1A1KDM4EHTTHDAC1HDAC6 | |
| Trimethylammonium SCHEMBL993437 | 0.80 | CYP2C19 (0.69) | ALDH1A1MEN1KMT2ATSHRMAPT | |
| SCHEMBL2571999 | 0.80 | FFAR1 (0.52) | ALDH1A1KDM4EHTTHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113337417-A | Agrobacterium capable of efficiently degrading ethyl carbamate and application thereof | 大连工业大学 | 2021-09-03 | — | — | CN | disclosed |
| CN-113174342-A | Strain for efficiently degrading ethyl carbamate and application thereof | 大连工业大学 | 2021-07-27 | — | — | CN | disclosed |
| US-8383813-B2 | Fused pyrrolocarbazoles | CEPHALON, INC. (US) | 2013-02-26 | — | — | US | disclosed |
| US-8383813-B2 | Fused pyrrolocarbazoles | CEPHALON, INC. (US) | 2013-02-26 | — | — | US | disclosed |
| US-20120004253-A1 | Novel Fused Pyrrolocarbazoles | CEPHALON, INC. (US) | 2012-01-05 | — | — | US | disclosed |
| US-20120004253-A1 | Novel Fused Pyrrolocarbazoles | CEPHALON, INC. (US) | 2012-01-05 | — | — | US | disclosed |
| US-8044064-B2 | Fused pyrrolocarbazoles | CEPHALON, INC. (US) | 2011-10-25 | — | — | US | disclosed |
| US-8044064-B2 | Fused pyrrolocarbazoles | CEPHALON, INC. (US) | 2011-10-25 | — | — | US | disclosed |
| US-20100152196-A1 | Novel Fused Pyrrolocarbazoles | CEPHALON, INC. (US) | 2010-06-17 | — | — | US | disclosed |
| US-20100152196-A1 | Novel Fused Pyrrolocarbazoles | CEPHALON, INC. (US) | 2010-06-17 | — | — | US | disclosed |
| US-7671064-B2 | Fused pyrrolocarbazoles | CEPHALON, INC. (US) | 2010-03-02 | — | — | US | disclosed |
| US-7671064-B2 | Fused pyrrolocarbazoles | CEPHALON, INC. (US) | 2010-03-02 | — | — | US | disclosed |
| US-7169802-B2 | Fused pyrrolocarbazoles | CEPHALON, INC. (US) | 2007-01-30 | — | — | US | disclosed |
| US-7169802-B2 | Fused pyrrolocarbazoles | CEPHALON, INC. (US) | 2007-01-30 | — | — | US | disclosed |
| WO-2005063763-A1 | NOVEL FUSED PYRROLOCARBAZOLES | CEPHALON, INC. (US) | 2005-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152196-A1 | Novel Fused Pyrrolocarbazoles | PC, PYCR1, CYP11B2 | ALDH1A1 467/4885KDM4E 3223/4885HTT 210/4885 |
| US-20120004253-A1 | Novel Fused Pyrrolocarbazoles | PC, PYCR1, CYP11B2 | ALDH1A1 467/4885KDM4E 3223/4885HTT 210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.