Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27565328 | 0.85 | KDM4E (0.43) | SLC6A3SLC6A4AXLSMN1; SMN2TSHR | |
| SCHEMBL27585156 | 0.84 | LMNA (0.48) | SLC6A3SLC6A4DHODHAXLSMN1; SMN2 | |
| SCHEMBL27585150 | 0.78 | MAPK1 (0.52) | DHODHSMN1; SMN2HTTKMT2AALDH1A1 | |
| SCHEMBL29094948 | 0.78 | FABP4 (0.54) | SLC6A3SLC6A4SMN1; SMN2TSHRMEN1 | |
| SCHEMBL27568452 | 0.77 | FTO (0.42) | SLC6A3SMN1; SMN2TSHRTDP1MEN1 | |
| SCHEMBL27341171 | 0.76 | PKN1 (0.52) | AXLSMN1; SMN2TSHRTDP1MEN1 | |
| SCHEMBL27454418 | 0.76 | ALDH1A1 (0.49) | SLC6A3SLC6A4SMN1; SMN2TSHRMEN1 | |
| SCHEMBL27585176 | 0.75 | MAP4K4 (0.48) | SLC6A3SLC6A4AXLSMN1; SMN2TSHR | |
| SCHEMBL27892517 | 0.74 | SMN1; SMN2 (0.44) | SLC6A3SLC6A4SMN1; SMN2TSHRTDP1 | |
| SCHEMBL27875977 | 0.73 | LOXL2 (0.53) | SLC6A3SLC6A4SMN1; SMN2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1392874-A | Cyclic amidine compounds | SUNTORY LTD (JP) | 2003-01-22 | — | — | CN | claimed |
| CN-1392874-A | Cyclic amidine compounds | SUNTORY LTD (JP) | 2003-01-22 | — | — | CN | disclosed |