Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 5/20 | 0.54 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423858 | 0.85 | CCR2 (0.74) | CCR2PLA2G10IDO1F10ALDH1A1 | |
| SCHEMBL7420717 | 0.80 | F10 (0.53) | IDO1F10ALDH1A1POLBKMT2A | |
| SCHEMBL3963187 | 0.76 | PLA2G10 (0.83) | CCR2PLA2G10F10GPR35 | |
| SCHEMBL5378162 | 0.73 | CCR2 (1.00) | CCR2PLA2G10F10ALDH1A1CYP1A2 | |
| SCHEMBL1647858 | 0.73 | PLA2G10 (0.50) | CCR2PLA2G10IDO1F10ALDH1A1 | |
| SCHEMBL7424288 | 0.72 | NOD2 (0.69) | CCR2IDO1F10ALDH1A1POLB | |
| SCHEMBL4600132 | 0.72 | CCR2 (0.61) | CCR2IDO1F10ALDH1A1GPR35 | |
| SCHEMBL7809796 | 0.72 | LMNA (0.52) | CCR2PLA2G10IDO1CNR2 | |
| SCHEMBL7803252 | 0.71 | IDO1 (0.45) | CCR2PLA2G10IDO1CNR2 | |
| SCHEMBL7812252 | 0.71 | IDO1 (0.51) | CCR2PLA2G10IDO1F10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1220681-C | Indole derivatives as XA factor inhibitors | AVENTIS MEDICINES DEUTSCHLAND (DE) | 2005-09-28 | — | — | CN | disclosed |
| CN-1283186-A | Indole derivatives as XA factor inhibitors | AWENTIS MEDICINES DEUTSCHLAND (DE) | 2001-02-07 | — | — | CN | disclosed |