Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | CCR2 | P41597 | 3/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423858 | 0.81 | CCR2 (0.74) | IDO1CCR2SRCKMT2AGABRA1 | |
| SCHEMBL7424288 | 0.78 | NOD2 (0.69) | IDO1CCR2SRCKMT2AGABRA1 | |
| SCHEMBL27204175 | 0.78 | BRD4 (0.56) | IDO1SRCKMT2AGABRA1GABRA5 | |
| SCHEMBL18258220 | 0.76 | ALDH1A1 (0.51) | IDO1CCR2SRCGABRA1GABRA5 | |
| SCHEMBL7803015 | 0.75 | SRC (0.48) | IDO1CCR2SRCGABRA1GABRA5 | |
| SCHEMBL7811906 | 0.72 | IDO1 (0.47) | IDO1CCR2SRCKMT2AGABRA1 | |
| SCHEMBL18247693 | 0.72 | GABRA5 (0.48) | IDO1CCR2SRCGABRA1GABRA5 | |
| SCHEMBL20853252 | 0.72 | SRC (0.47) | IDO1CCR2SRCGABRA1GABRA5 | |
| SCHEMBL30229394 | 0.72 | GABRA5 (0.48) | IDO1CCR2SRCGABRA1GABRA5 | |
| SCHEMBL7420717 | 0.71 | F10 (0.53) | IDO1KMT2ALMNATP53NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949259-B1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6184238-B1 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0949259-A1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-10-13 | — | — | EP | disclosed |