SCHEMBL275682

SCHEMBL275682

O=C(O)c1ccccc1NCl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 3/20 0.57
ALDH1A1 P00352 3/20 0.56
ALOX15 P16050 1/20 0.56
HPGD P15428 2/20 0.53
FABP3 P05413 2/20 0.53
FABP5 Q01469 2/20 0.53
HSD17B10 Q99714 1/20 0.53
PBRM1 Q86U86 1/20 0.53
KMT2A Q03164 5/20 0.52
MEN1 O00255 4/20 0.52
PKM P14618 1/20 0.52
KDM4E B2RXH2 1/20 0.52
AGTR1 P30556 1/20 0.52
RAB9A P51151 1/20 0.52
TTR P02766 2/20 0.51
LMNA P02545 2/20 0.51
CYP1A2 P05177 2/20 0.51
CYP3A4 P08684 2/20 0.51
CYP2C9 P11712 2/20 0.51
PTGS2 P35354 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anthranilic Acid SCHEMBL28128512 0.89 CDC25B (0.55) FABP4ALDH1A1ALOX15HPGDFABP3
SCHEMBL22914709 0.83 FABP4 (0.53) FABP4ALDH1A1ALOX15HPGDFABP3
SCHEMBL12041920 0.83 PBRM1 (0.54) FABP4ALDH1A1ALOX15HPGDFABP3
SCHEMBL28009555 0.82 ALDH1A1 (0.50) FABP4ALDH1A1ALOX15HPGDFABP3
SCHEMBL355549 0.81 FABP4 (0.80) FABP4ALDH1A1ALOX15HPGDFABP3
SCHEMBL7610425 0.81 ALDH1A1 (0.62) FABP4ALDH1A1ALOX15HPGDFABP3
SCHEMBL30320327 0.81 FABP4 (0.80) FABP4ALDH1A1ALOX15HPGDFABP3
SCHEMBL9770758 0.80 KDM4E (0.58) ALDH1A1HPGDHSD17B10KMT2AMEN1
SCHEMBL143766 0.79 ALDH1A1 (0.59) FABP4ALDH1A1ALOX15HPGDFABP3
SCHEMBL222251 0.79 ALDH1A1 (0.59) FABP4ALDH1A1ALOX15HPGDFABP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104112603-B Polypyrrole-titanium dioxide or titanium nitride-polyaniline coaxial three-layer nanotube array composite material, and preparation method and application thereof 东南大学 2017-05-03 CN claimed
CN-106431946-A Synthetic method of lobenzarit drug intermediate N-o-carboxylphenyl-4-chlorin-2-aminobenzoic acid 厦门安普顿信息科技有限公司 2017-02-22 CN claimed
CN-104112603-A Polypyrrole-titanium dioxide or titanium nitride-polyaniline coaxial three-layer nanotube array composite material, and preparation method and application thereof UNIV SOUTHEAST 2014-10-22 CN claimed
EP-2120555-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN Heller, Adam (US) 2009-11-25 EP claimed
US-20080287866-A1 Methods and compositions for the treatment of pain HELLER ADAM 2008-11-20 US claimed
WO-2008094664-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN HELLER ADAM (US) 2008-08-07 WO claimed
US-6541653-B2 Reacting an amine, alcohol, oxygen, and carbon monoxide in the gaseous state in the presence of a solid catalytic system of a group VIII metal catalysts and/or copper-based catalysts with halide promoters AKRON, UNIVERSITY OF, THE 2003-04-01 US claimed
US-20020183541-A1 SYNTHESIS OF CARBAMATE THROUGH LOW PRESSURE HETEROGENEOUS OXIDATIVE CARBONYLATION OF AMINES AKRON, UNIVERSITY OF, THE 2002-12-05 US claimed
WO-2002088050-A2 SYNTHESIS OF CARBAMATE THROUGH LOW PRESSURE HETEROGENEOUS OXIDATIVE CARBONYLATION OF AMINES THE UNIVERSITY OF AKRON (US) 2002-11-07 WO claimed
US-3991107-A Haloamine transfer NATIONAL PATENT DEVELOPMENT CORPORATION (US) 1976-11-09 US claimed
JP-4224549-A None JP disclosed
US-20240091121-A1 PHOSPHONATES AND N-HALAMINES COMPOSITIONS FOR TARTAR REMOVAL O.Y.M. INNOVATION LTD. (IL) 2024-03-21 US disclosed
EP-4274539-A2 PHOSPHONATES AND N-HALAMINES COMPOSITIONS FOR TARTAR REMOVAL O.Y.M. Innovation Ltd. (IL) 2023-11-15 EP disclosed
CN-116710046-A Phosphonic acid and N-halamine compositions for tartar removal O.Y.M.创新有限公司 2023-09-05 CN disclosed
CN-111721856-B Method for detecting pyrethroid pesticide metabolite in tea 中国农业科学院茶叶研究所 2022-12-13 CN disclosed
EP-0018100-A2 Substituted aromatic biologically active compound, a process for its preparation and its use as biocide IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-10-29 EP disclosed
EP-0015065-A1 Pyrazolo (5,1-b) quinazolin-9(4H)-one derivatives, process for their preparation and pharmaceutical compositions containing them WARNER-LAMBERT COMPANY (US) 1980-09-03 EP disclosed
US-4101429-A ZINC DIALKYLDITHIOPHOSPHATE, DIMER ACID, AND REACTION PRODUCT OF A ALKENYL SUCCINIC ANHYDRIDE-MODIFIED POLYALKYLENIMINE AND A MONOCARBOXYLIC ACID SHELL OIL COMPANY (US) 1978-07-18 US disclosed
US-3991107-A Haloamine transfer NATIONAL PATENT DEVELOPMENT CORPORATION (US) 1976-11-09 US disclosed
US-3943628-A Spoon excavator for applying chemically acting tooth decay attacking fluid KRONMAN JOSEPH H 1976-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020183541-A1 SYNTHESIS OF CARBAMATE THROUGH LOW PRESSURE HETEROGENEOUS OXIDATIVE CARBONYLATION OF AMINES SOD1, CAT, CA4 FABP4 4175/4885ALDH1A1 1280/4885ALOX15 2877/4885
US-20240091121-A1 PHOSPHONATES AND N-HALAMINES COMPOSITIONS FOR TARTAR REMOVAL PHOSPHO1, PHPT1, PTMS FABP4 2008/4885ALDH1A1 4414/4885ALOX15 4635/4885
US-20080287866-A1 Methods and compositions for the treatment of pain ACHE, S100P, P2RX3 FABP4 676/4885ALDH1A1 2612/4885ALOX15 442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.