Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | RAF1 | P04049 | 1/20 | 0.51 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10773023 | 0.88 | TSHR (0.61) | TAAR1SMN1; SMN2TSHRTP53EPHX1 | |
| SCHEMBL305498 | 0.80 | TAAR1 (1.00) | TAAR1HTTALDH1A1MDM2SMN1; SMN2 | |
| SCHEMBL23069097 | 0.77 | TAAR1 (0.85) | TAAR1HTTMDM2SMN1; SMN2TSHR | |
| SCHEMBL5177511 | 0.76 | ALDH1A1 (0.65) | TAAR1HTTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL27634795 | 0.76 | JAK2 (0.56) | HTTALDH1A1SMN1; SMN2EPHX1LMNA | |
| SCHEMBL11257766 | 0.75 | NPC1 (0.57) | TAAR1HTTSMN1; SMN2TSHRTP53 | |
| SCHEMBL11413702 | 0.74 | SMN1; SMN2 (0.64) | TAAR1HTTALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL22368588 | 0.74 | SNCA (0.54) | HTTALDH1A1SMN1; SMN2TSHRTP53 | |
| SCHEMBL6230258 | 0.74 | CDK5 (0.56) | SMN1; SMN2TSHRTP53EPHX1EPHX2 | |
| SCHEMBL25825682 | 0.74 | TAAR1 (0.85) | TAAR1HTTMDM2SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1341098-A | Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors | BAYER AG (US) | 2002-03-20 | — | — | CN | claimed |