Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 0.51 |
| ▸ | HTR2C | P28335 | 6/20 | 0.50 |
| ▸ | HTR2B | P41595 | 5/20 | 0.50 |
| ▸ | HTR2A | P28223 | 5/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12558826 | 0.79 | HTR2C (0.69) | HTR6HTR2CHTR2BHTR2AHTR1D | |
| SCHEMBL13592835 | 0.76 | HTR6 (0.53) | HTR6HTR2CHTR2BHTR2AHTR1D | |
| Hydrochloric Acid SCHEMBL3790913 | 0.75 | HTR6 (0.52) | HTR6HTR2CHTR2BHTR2AHTR1D | |
| SCHEMBL3804057 | 0.74 | HTR1A (0.46) | HTR6HTR2CHTR2BHTR2AHTR1D | |
| SCHEMBL2758319 | 0.73 | HTR2C (0.66) | HTR6HTR2CHTR2BHTR2AHTR1D | |
| SCHEMBL12558970 | 0.72 | HTR6 (0.45) | HTR6HTR2CHTR2BHTR2AHTR1D | |
| SCHEMBL2758321 | 0.72 | HTR6 (0.57) | HTR6HTR2CHTR2BHTR2AHTR1D | |
| SCHEMBL3804932 | 0.71 | HTR2C (0.63) | HTR6HTR2CHTR2BHTR2AHTR1D | |
| SCHEMBL16286341 | 0.71 | HTR6 (0.44) | HTR6HTR2CHTR2BHTR2AHTR1D | |
| SCHEMBL13592775 | 0.71 | HTR6 (0.50) | HTR6HTR2CHTR2BHTR2AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9302990-B2 | Fluorination of aromatic ring systems | NUTECH VENTURES (US) | 2016-04-05 | — | — | US | disclosed |
| US-8546578-B2 | Iodonium Cyclophanes for SECURE arene functionalization | NUTECH VENTURES (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120004417-A1 | FLUORINATION OF AROMATIC RING SYSTEMS | NATIONAL SCIENCE FOUNDATION | 2012-01-05 | — | — | US | disclosed |
| US-20110313170-A1 | Fluorination of Aromatic Ring Systems | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2011-12-22 | — | — | US | disclosed |
| US-20110190505-A1 | Iodonium Cyclophanes for SECURE Arene Functionalization | NATIONAL SCIENCE FOUNDATION | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004417-A1 | FLUORINATION OF AROMATIC RING SYSTEMS | PFAS, SLC43A1, DDC | HTR6 599/4885HTR2C 460/4885HTR2B 1066/4885 |
| US-20110190505-A1 | Iodonium Cyclophanes for SECURE Arene Functionalization | ABL1, SLC7A5, DDC | HTR6 1739/4885HTR2C 829/4885HTR2B 1501/4885 |
| US-20110313170-A1 | Fluorination of Aromatic Ring Systems | PFAS, SLC43A1, DDC | HTR6 599/4885HTR2C 460/4885HTR2B 1066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.