Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.55 |
| ▸ | HTR6 | P50406 | 13/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2758324 | 0.89 | HTR1D (0.70) | HTR1DHTR6HTR2AHTR2CHTR2B | |
| SCHEMBL23913563 | 0.80 | HTR1D (0.54) | HTR1DHTR2ACYP1A2CYP2C19 | |
| SCHEMBL25624145 | 0.77 | HTR6 (0.80) | HTR1DHTR6HTR2A | |
| SCHEMBL12850609 | 0.75 | HTR2A (0.65) | HTR1DHTR6HTR2AHTR2CHTR2B | |
| SCHEMBL2758321 | 0.73 | HTR6 (0.57) | HTR1DHTR6HTR2AHTR2CHTR2B | |
| SCHEMBL26144296 | 0.73 | HTR1D (0.47) | HTR1D | |
| SCHEMBL24123873 | 0.72 | HTR1D (0.56) | HTR1DCYP1A2CYP2C19KCNH2 | |
| SCHEMBL11059665 | 0.71 | HTR1D (0.48) | HTR1D | |
| SCHEMBL26662793 | 0.71 | HTR1D (1.00) | HTR1DHTR6HTR2AHTR2C | |
| SCHEMBL3348930 | 0.71 | HTR6 (0.66) | HTR1DHTR6HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9302990-B2 | Fluorination of aromatic ring systems | NUTECH VENTURES (US) | 2016-04-05 | — | — | US | disclosed |
| US-8546578-B2 | Iodonium Cyclophanes for SECURE arene functionalization | NUTECH VENTURES (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120004417-A1 | FLUORINATION OF AROMATIC RING SYSTEMS | NATIONAL SCIENCE FOUNDATION | 2012-01-05 | — | — | US | disclosed |
| US-20110313170-A1 | Fluorination of Aromatic Ring Systems | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2011-12-22 | — | — | US | disclosed |
| US-20110190505-A1 | Iodonium Cyclophanes for SECURE Arene Functionalization | NATIONAL SCIENCE FOUNDATION | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004417-A1 | FLUORINATION OF AROMATIC RING SYSTEMS | PFAS, SLC43A1, DDC | HTR1D 1356/4885HTR6 599/4885HTR2A 1085/4885 |
| US-20110190505-A1 | Iodonium Cyclophanes for SECURE Arene Functionalization | ABL1, SLC7A5, DDC | HTR1D 2184/4885HTR6 1739/4885HTR2A 2428/4885 |
| US-20110313170-A1 | Fluorination of Aromatic Ring Systems | PFAS, SLC43A1, DDC | HTR1D 1356/4885HTR6 599/4885HTR2A 1085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.