Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | APP | P05067 | 2/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4485687 | 0.98 | TDP1 (0.62) | TDP1APPALOX5NPC1RAB9A | |
| SCHEMBL3821350 | 0.91 | TDP1 (0.60) | TDP1APPNPC1RAB9AALDH1A1 | |
| SCHEMBL4486787 | 0.89 | TDP1 (0.58) | TDP1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4477247 | 0.88 | TDP1 (0.57) | TDP1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL22832718 | 0.88 | TDP1 (0.81) | TDP1APPALOX5NPC1RAB9A | |
| SCHEMBL28118444 | 0.86 | TDP1 (0.72) | TDP1APPALOX5NPC1RAB9A | |
| SCHEMBL1960554 | 0.84 | TDP1 (0.63) | TDP1APPALOX5NPC1RAB9A | |
| SCHEMBL1177227 | 0.83 | ALDH1A1 (0.58) | TDP1L3MBTL1ALDH1A1MAPK1HCAR2 | |
| SCHEMBL1719207 | 0.83 | TDP1 (0.72) | TDP1APPALOX5NPC1RAB9A | |
| SCHEMBL9367557 | 0.83 | TDP1 (0.92) | TDP1APPALOX5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12539285-B2 | Therapeutic agent for hypertrophic cardiomyopathy | JUNTENDO EDUCATIONAL FOUNDATION (JP) | 2026-02-03 | — | — | US | disclosed |
| US-20240082189-A1 | THERAPEUTIC AGENT FOR HYPERTROPHIC CARDIOMYOPATHY | JUNTENDO EDUCATIONAL FOUNDATION (JP) | 2024-03-14 | — | — | US | disclosed |
| EP-4309651-A1 | THERAPEUTIC AGENT FOR HYPERTROPHIC CARDIOMYOPATHY | Juntendo Educational Foundation (JP) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022158591-A1 | THERAPEUTIC AGENT FOR HYPERTROPHIC CARDIOMYOPATHY | 学校法人順天堂 | 2022-07-28 | — | — | WO | disclosed |
| EP-1743621-B1 | HAIR RESTORER | COSMO OIL CO LTD (JP) | 2014-03-05 | — | — | EP | disclosed |
| US-8632759-B2 | Hair restorer | COSMO OIL CO., LTD. (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20120122974-A1 | HAIR RESTORER | COSMO OIL CO., LTD. (JP) | 2012-05-17 | — | — | US | disclosed |
| US-8133479-B2 | Hair restorer | COSMO OIL CO., LTD. (JP) | 2012-03-13 | — | — | US | disclosed |
| EP-0995448-B1 | COMPOUND FOR DIAGNOSING MALIGNANT TUMORS | SBI ALAPROMO CO LTD (JP) | 2009-09-02 | — | — | EP | disclosed |
| US-7563819-B1 | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy | PHOTOCURE ASA (NO) | 2009-07-21 | — | — | US | disclosed |
| EP-1313695-B1 | ESTERS OF 5-AMINOLEVULINIC ACID AS PHOTOSENSITIZING AGENTS IN PHOTOCHEMOTHERAPY | PHOTOCURE ASA (NO) | 2006-12-27 | — | — | EP | disclosed |
| US-7135162-B2 | Agent for diagnosing and treating malignant tumors | COSMO RESEARCH INSTITUTE (JP) | 2006-11-14 | — | — | US | disclosed |
| US-6992107-B1 | Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy | PHOTOCURE ASA (NO) | 2006-01-31 | — | — | US | disclosed |
| US-6905671-B1 | Diagnostic agents and remedies for malignant tumors | COSMO RESEARCH INSTITUTE (JP) | 2005-06-14 | — | — | US | disclosed |
| US-20050107471-A1 | NEW ESTERS OF 5-AMINOLEVULINIC ACID AND THEIR USE AS PHOTOSENSITIZING COMPOUNDS IN PHOTOCHEMOTHERAPY | GIERSKCKY KARL E (NO) | 2005-05-19 | — | — | US | disclosed |
| US-20040106679-A1 | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy | PHOTOCURE ASA (NO) | 2004-06-03 | — | — | US | disclosed |
| EP-1313695-A1 | ESTERS OF 5-AMINOLEVULINIC ACID AS PHOTOSENSITIZING AGENTS IN PHOTOCHEMOTHERAPY | Photocure ASA (NO) | 2003-05-28 | — | — | EP | disclosed |
| US-20030065029-A1 | Agent for diagnosing and treating malignant tumors | COSMO RESEARCH INSTITUTE, COSMO OIL CO., LTD. | 2003-04-03 | — | — | US | disclosed |
| WO-2002010120-A1 | ESTERS OF 5-AMINOLEVULINIC ACID AS PHOTOSENSITIZING AGENTS IN PHOTOCHEMOTHERAPY | PHOTOCURE ASA (NO) | 2002-02-07 | — | — | WO | disclosed |
| EP-0995448-A1 | DIAGNOSTIC AGENTS AND REMEDIES FOR MALIGNANT TUMORS | Cosmo Research Institute (JP) | 2000-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12539285-B2 | Therapeutic agent for hypertrophic cardiomyopathy | ALAD, TNNT2, MYH2 | TDP1 2171/4885APP 1365/4885ALOX5 171/4885 |
| US-20030065029-A1 | Agent for diagnosing and treating malignant tumors | ALAD, VHL, AADAT | TDP1 4443/4885APP 1429/4885ALOX5 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.