Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 2/20 | 0.40 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | BID | P55957 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4880816 | 0.82 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1HSD17B10ALOX15 | |
| SCHEMBL4430996 | 0.81 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1ALOX15POLB | |
| SCHEMBL1897597 | 0.81 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1ALOX15POLB | |
| SCHEMBL1028400 | 0.80 | LGMN (0.50) | LGMNMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL8213975 | 0.80 | ALDH1A1 (0.42) | LGMNALDH1A1HSD17B10ALOX15MAPK10 | |
| SCHEMBL4113163 | 0.78 | DRD2 (0.51) | ALDH1A1POLBMAPTKDM4EL3MBTL1 | |
| SCHEMBL2125041 | 0.78 | MAPT (0.50) | LGMNMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL4485709 | 0.77 | CHRM1 (0.37) | ALDH1A1ADRB1KDM4EL3MBTL1 | |
| SCHEMBL17838712 | 0.74 | KDM4E (0.41) | ALDH1A1MAPK10MAPTKDM4E | |
| SCHEMBL27769716 | 0.74 | CYP2D6 (0.45) | MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1538951-A | Omega-aminoalkylamides of R-2-aryl-propionic acids as inhibitors of chemotaxis of polymorphonucleate and mononucleate cells | ��ķ�ɷ�����˾ | 2004-10-20 | — | — | CN | claimed |
| CN-1538951-B | Omega-aminoalkylamides of R-2-aryl-propionic acids as inhibitors of chemotaxis of polymorphonucleate and mononucleate cells | DOMPE SPA | 2013-08-28 | — | — | CN | disclosed |
| CN-1538951-A | Omega-aminoalkylamides of R-2-aryl-propionic acids as inhibitors of chemotaxis of polymorphonucleate and mononucleate cells | ��ķ�ɷ�����˾ | 2004-10-20 | — | — | CN | disclosed |