Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 6/20 | 0.37 |
| ▸ | NOS2 | P35228 | 6/20 | 0.37 |
| ▸ | NOS3 | P29474 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27606385 | 0.85 | HRH3 (0.39) | LOXL2 | |
| SCHEMBL27588582 | 0.83 | MAOB (0.43) | ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL27606468 | 0.79 | ENPP2 (0.44) | ENPP2ALDH1A1CYP3A4NFKB1 | |
| SCHEMBL27606407 | 0.79 | ALDH1A1 (0.40) | NOS1NOS2ALDH1A1TLR8 | |
| SCHEMBL486262 | 0.77 | CALM1 (0.46) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL20961846 | 0.74 | LOXL2 (0.60) | PNMTENPP2LOXL2PRMT6NOS1 | |
| SCHEMBL27588484 | 0.72 | CDK8 (0.42) | PNMTENPP2LOXL2PRMT6NOS1 | |
| SCHEMBL30350846 | 0.72 | LOXL2 (0.63) | PNMTENPP2LOXL2PRMT6NOS1 | |
| SCHEMBL36008 | 0.72 | LOXL2 (0.71) | PNMTENPP2LOXL2PRMT6NOS1 | |
| SCHEMBL10422276 | 0.72 | LOXL2 (0.71) | PNMTENPP2LOXL2PRMT6NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1553900-A | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents | ��ʱ��ʩ����ҩ��˾ | 2004-12-08 | — | — | CN | disclosed |