Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.34 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27379419 | 0.77 | GRM6 (0.40) | GRM6CISD2CYP2C19 | |
| SCHEMBL27379293 | 0.77 | GRM6 (0.40) | GRM6CISD2CYP2C19 | |
| SCHEMBL30755194 | 0.75 | NR1H2 (0.40) | GRM6POLBCISD2CYP2C19 | |
| SCHEMBL993670 | 0.73 | TSHR (0.34) | ACHEKDM4EALDH1A1GAATSHR | |
| SCHEMBL27606975 | 0.73 | CYP4F2 (0.41) | KDM4EALDH1A1GAATSHRRAB9A | |
| SCHEMBL12723861 | 0.71 | ACHE (0.57) | ACHEPOLBKDM4EALDH1A1GAA | |
| SCHEMBL16680874 | 0.70 | GRM6 (0.40) | GRM6POLBKDM4EALDH1A1GAA | |
| SCHEMBL16115116 | 0.70 | CFD (0.45) | GRM6KDM4EALDH1A1GAATSHR | |
| SCHEMBL24195886 | 0.69 | KDM4E (0.47) | ACHEKDM4EALDH1A1GAATSHR | |
| SCHEMBL27770533 | 0.69 | GRM6 (0.41) | ACHEGRM6POLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101284773-A | Carboxylic acid derivative compounds and drugs comprising these compounds as the active ingredient | ONO PHARMACEUTICAL CO (JP) | 2008-10-15 | — | — | CN | disclosed |
| CN-1551866-A | Carboxylic acid derivative compounds and drugs containing these compounds as active ingredient | СҰҩƷ��ҵ��ʽ���� | 2004-12-01 | — | — | CN | disclosed |